Domain-specific transition questions demonstrated higher validity than global transition questions as anchors for clinically important improvement

Journal of Clinical Epidemiology
Michael M WardMaria Alba

Abstract

Estimates of minimal clinically important differences in health measures may be affected by the anchor used. We examined if domain-specific transition questions had higher construct validity than global health transition questions as anchors for measures in a given domain. In a prospective study of 249 patients with rheumatoid arthritis, we examined changes in pain, physical function, joint swelling, stiffness, fatigue, and depression with treatment. We related these changes to a domain-specific transition question, global arthritis transition question, and the Short Form-36 (SF-36) health transition item. Changes in all six clinical measures were more highly correlated with the domain-specific transition questions than with the global arthritis question and SF-36 transition question. Discrimination between patients who improved or not was also better using domain-specific questions. Estimates of minimal clinically important improvement (MCII) differed with the anchor when these were based on mean changes. MCII estimates from receiver operating characteristic curve analysis were not influenced by the choice of anchor when anchors had high agreement. Domain-specific transition questions had higher construct validity as anchors f...Continue Reading

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Citations

Mar 16, 2016·The Journal of Pain : Official Journal of the American Pain Society·Alessandro ChiarottoPaolo Pillastrini
Jul 9, 2016·BMC Medical Research Methodology·Åsa NordinAnna Dencker
Nov 28, 2018·The American Journal of Sports Medicine·Dean WangRiley J Williams
May 29, 2020·BMC Musculoskeletal Disorders·Tarjei RysstadAnne Therese Tveter
Mar 17, 2017·The American Journal of Sports Medicine·Benedict U NwachukwuAnil S Ranawat
Dec 20, 2017·The Journal of Orthopaedic and Sports Physical Therapy·Alessandro ChiarottoMarco Monticone
May 6, 2020·Health and Quality of Life Outcomes·Bingqing BaiFangran Xin
Jan 5, 2018·Health and Quality of Life Outcomes·Michael M WardMaria Alba
Oct 24, 2017·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·C ParaiH Brisby
Apr 7, 2020·Journal of Shoulder and Elbow Surgery·Ian A JonesC Thomas Vangsness

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