Dominance genetic variance for traits under directional selection in Drosophila serrata

Genetics
Jacqueline L Sztepanacz, M W Blows

Abstract

In contrast to our growing understanding of patterns of additive genetic variance in single- and multi-trait combinations, the relative contribution of nonadditive genetic variance, particularly dominance variance, to multivariate phenotypes is largely unknown. While mechanisms for the evolution of dominance genetic variance have been, and to some degree remain, subject to debate, the pervasiveness of dominance is widely recognized and may play a key role in several evolutionary processes. Theoretical and empirical evidence suggests that the contribution of dominance variance to phenotypic variance may increase with the correlation between a trait and fitness; however, direct tests of this hypothesis are few. Using a multigenerational breeding design in an unmanipulated population of Drosophila serrata, we estimated additive and dominance genetic covariance matrices for multivariate wing-shape phenotypes, together with a comprehensive measure of fitness, to determine whether there is an association between directional selection and dominance variance. Fitness, a trait unequivocally under directional selection, had no detectable additive genetic variance, but significant dominance genetic variance contributing 32% of the phenoty...Continue Reading

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Citations

Jun 18, 2019·Evolution; International Journal of Organic Evolution·Jacqueline L Sztepanacz, David Houle
Nov 3, 2020·Evolution; International Journal of Organic Evolution·Eva L KochFrédéric Guillaume
Jan 17, 2021·Heredity·Jorge F HenriquesJordi Moya-Laraño
Feb 22, 2021·Theoretical Population Biology·Steinar Engen, Bernt-Erik Sæther
Feb 28, 2021·Evolution; International Journal of Organic Evolution·Jacqueline L Sztepanacz, David Houle
Jul 31, 2021·Proceedings of the National Academy of Sciences of the United States of America·Robert J DugandKatrina McGuigan

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