PMID: 6987512Jan 1, 1980Paper

Dominant lethal mutation induced in male rats by 1,2-dibromo-3-chloropropane (DBCP)

Mutation Research
S TeramotoY Shirasu

Abstract

1,2-Dibromoethane (DBE) and 1,2-dibromo-3-chloropropane (DBCP), soil fumigants, were investigated for their potential mutagenicity by dominant lethal studies in the rat and mouse. Dominant lethal mutation was induced by DBE in neither of the species. DBCP, on the other hand, induced dominant lethals in rats in the post-meiotic stage of spermatogenesis, especially in the early spermatid stage. However, DBCP did not cause dominant lethals in mice.

References

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Jul 1, 1975·Bulletin of Environmental Contamination and Toxicology·H S Rosenkranz
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Citations

Jan 1, 1983·American Journal of Industrial Medicine·D R Mattison
Mar 1, 1981·The Science of the Total Environment·H BabichG Stotzky
Jul 1, 1989·Mutation Research·S Teramoto, Y Shirasu
Jun 1, 1986·Mutation Research·Y F SasakiK Tutikawa
Nov 1, 1989·Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology·R E MorrisseyJ J Heindel
Jan 1, 1988·Reproductive Toxicology·D Whorton, D Foliart
Sep 1, 1982·Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology·K S RaoC M Parker
Jan 1, 1983·Environmental Health Perspectives·J E Huff
Apr 1, 1986·Environmental Health Perspectives·C A KimmelV Frankos
Jul 1, 1990·Toxicology and Applied Pharmacology·R E ChapinL T Burka
Jan 7, 2015·Congenital Anomalies·Keitaro HirawatariHideo Gotoh
Jan 1, 1982·Environmental Mutagenesis·P G Kale, J W Baum
Oct 1, 1982·Journal of Applied Toxicology : JAT·C C Willhite
Sep 2, 2018·Mammalian Genome : Official Journal of the International Mammalian Genome Society·Hideo GotohShigeharu Wakana
Jan 1, 1984·Environmental Mutagenesis·E F Oakberg, C C Cummings

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