Abstract
Autopsy and clinical studies were performed in a family with dominantly inherited retinitis pigmentosa. The eyes of two senior members of the family were obtained for histopathologic study, while three other family members were studied clinically. All family members studied had visual field loss, nyctalopia, and a spectrum of pigmentary disruption. There was variable expressivity of pigmentary migration, foveal atrophic changes, surface wrinkling retinopathy, choriocapillaris atrophy, drusen, vitreous synchysis, and optic pallor. Three specific zones of retinal and retinal pigment epithelial changes were identified histopathologically. A clinicopathologic correlation is presented.
References
Dec 31, 1977·Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Albrecht Von Graefe's Archive for Clinical and Experimental Ophthalmology·R Y Foos
May 1, 1977·Archives of Ophthalmology·G A FishmanJ Maggiano
Nov 1, 1977·Archives of Ophthalmology·G A FishmanM Fishman
Sep 1, 1977·The British Journal of Ophthalmology·R I HansenP Henkind
May 1, 1976·The British Journal of Ophthalmology·S H Sarks
Aug 1, 1974·American Journal of Ophthalmology·E R Crouch, D J Apple
Jun 1, 1969·The American Journal of Anatomy·R G Frederickson, F N Low
Aug 1, 1981·Investigative Ophthalmology & Visual Science·R B Szamier
Nov 1, 1981·American Journal of Ophthalmology·J V BastekJ Heckenlively
Jan 1, 1956·The British Journal of Ophthalmology·D R LUCAS
Jan 1, 1930·Transactions of the American Ophthalmological Society·F H Verhoeff
Citations
Jun 15, 1986·American Journal of Ophthalmology·D M AlbertJ L Craft
Dec 1, 1989·Ophthalmology·M F GoldbergG A Fishman
Jan 1, 1994·Ophthalmology·D M BrosnahanH M Hammer
Dec 1, 1988·Ophthalmology·D A NewsomeP M Pitha-Rowe
Aug 1, 1985·Ophthalmology·M M RodriguesG J Chader
Mar 27, 2012·Micron : the International Research and Review Journal for Microscopy·Tapas Chandra Nag, Shashi Wadhwa
Mar 14, 2012·Micron : the International Research and Review Journal for Microscopy·Tapas Chandra Nag, Shashi Wadhwa
Oct 17, 2015·Documenta Ophthalmologica. Advances in Ophthalmology·G H YapA Chia
Jul 1, 1988·Indian Journal of Ophthalmology·M K Singh
May 1, 1999·Experimental Neurology·T DasG N Rao
Dec 1, 1994·Nature Genetics·B H WeberU Felbor
Jan 1, 1986·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·J DuvallJ Marshall
Jan 1, 1987·Journal of Ocular Pharmacology·D A NewsomeN G Bazan
Jun 1, 1994·Ophthalmic Genetics·A PiantanidaR Brancato
Nov 1, 1988·Survey of Ophthalmology·R A Pagon