Domino Reactions Containing Different Types of Heck Reactions for Selective 3,3- and 1,3-Diarylations of Propenol with Aryl Halides by Triple Catalysis

The Journal of Organic Chemistry
Zhi-Qiang ZhuZhi-Zhen Huang

Abstract

A new domino Heck-isomerization/Saegusa/Heck reaction of propenol with aryl iodides has been developed for the synthesis of 3,3-diaryl propenals by triple transition-metal catalysis. Moreover, we also developed the domino Heck-isomerization/Heck-type reaction of propenol with aryl iodides for the synthesis of 1,3-diaryl propanones by double transition-metal catalysis and the mediation of secondary amine or triple transition metal catalysis and aminocatalysis.

References

Aug 1, 1989·Journal of Medicinal Chemistry·R W GuthrieH Crowley
Jan 1, 1994·Journal of Natural Products·J OrjalaT Rali
Dec 2, 1999·Journal of Natural Products·D H SilvaM Yoshida
Aug 24, 2000·Accounts of Chemical Research·S Ikeda
Dec 26, 2001·Chemical Reviews·I P Beletskaya, A V Cheprakov
Feb 1, 1996·Chemical Reviews·Lutz F. Tietze
Jul 11, 2003·Bioorganic & Medicinal Chemistry Letters·Phaik-Eng SumTarek S Mansour
Nov 3, 2005·Bioorganic & Medicinal Chemistry·Sarot CheenprachaSupinya Tewtrakul
Nov 1, 2006·Angewandte Chemie·K C NicolaouPaul G Bulger
Dec 15, 2006·Journal of the American Chemical Society·Cheol-Min ParkSteven W Elmore
Jan 17, 2007·Angewandte Chemie·Dieter EndersMatthias R M Hüttl
Mar 6, 2007·The Journal of Organic Chemistry·Vincenzo CalòValentina Ferola
Jul 19, 2008·Journal of the American Chemical Society·Jiwu RuanJianliang Xiao
Oct 23, 2009·Chemical Society Reviews·K C Nicolaou, Jason S Chen
Nov 19, 2009·ChemMedChem·Athanasios PapakyriakouDionisios Vourloumis
Dec 24, 2009·Angewandte Chemie·Bernhard WestermannSander S van Berkel
Jan 13, 2010·Chemical Communications : Chem Comm·Jie LiuJian Li
Dec 3, 2010·Nature Chemistry·Christoph GrondalDieter Enders
Feb 19, 2011·Chemical Communications : Chem Comm·Chang-Shan GuoZhi-Zhen Huang
Nov 20, 2012·Chemical Reviews·Hélène Pellissier

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.