Donation after cardiac death in Queensland: review of the pilot project

Anaesthesia and Intensive Care
R KumarJ F Fraser

Abstract

Organ transplantation is a viable therapeutic option for patients with endstage organ failure when other therapies have been exhausted. Donation after cardiac death (DCD) is re-emerging as a potential option to expand the donor pool to meet an increasing demand for organ transplantation. In this review, we evaluate the evolution of the Queensland DCD pilot project since its inception in August 2008. A retrospective analysis of registry data from Australia and New Zealand Organ Donation (ANZOD) and DonateLife Queensland was performed to collect information relating to donor characteristics, DCD process and outcomes. Data was compared with the ANZOD registry annual reports from 2008 to 2010. Twenty-three (82%) out of 28 potential DCD organ donors were successful in donating their organs. The median time from presentation to reaching consensus to withdraw cardiorespiratory support was four days (interquartile range three to eight days). The median time from withdrawal to death was 20 minutes (interquartile range 18 to 25 minutes), and the median warm ischaemia time was 17 minutes (interquartile range 14 to 19 minutes). DCD donors represented 16% (23) of the 144 deceased donors over the study period and provided approximately 10% (...Continue Reading

References

Dec 1, 1987·The Journal of Neuroscience Nursing : Journal of the American Association of Neuroscience Nurses·M R Bartucci
Feb 6, 1997·The New England Journal of Medicine·P J Hauptman, K J O'Connor
Apr 15, 1997·Transplantation·G Kootstra
May 8, 1993·Kennedy Institute of Ethics Journal·M A DeVitaA Grenvik
Mar 17, 2004·Intensive Care Medicine·Helen Ingrid Opdam, William Silvester
Sep 24, 2005·Transplantation·Richard J HowardDanielle L Cornell
Jan 24, 2006·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·J L BernatF L Delmonico
Feb 24, 2006·Journal of Health Economics·Alberto Abadie, Sebastien Gay
Aug 22, 2006·Transplant International : Official Journal of the European Society for Organ Transplantation·Jeremy ChapmanGunnar Tufveson
Aug 8, 2007·The Medical Journal of Australia·Bernadette Richards, Wendy A Rogers
Apr 24, 2008·Critical Care Medicine·Robert D TruogUNKNOWN American Academy of Critical Care Medicine
May 28, 2008·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Gregory I SnellTakahiro Oto
Feb 25, 2009·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Jacob A AkohMartin B Walker
Mar 10, 2009·Critical Care Clinics·Peter K Linden
May 13, 2009·ANZ Journal of Surgery·Nancy SuhHenry Pleass
Jul 25, 2009·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·D J ReichUNKNOWN ASTS Standards on Organ Transplantation Committee
Jan 12, 2010·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·C MoersR J Ploeg
Feb 4, 2010·Critical Care Medicine·James L BernatDouglas B White
Apr 24, 2010·The Journal of Thoracic and Cardiovascular Surgery·Nilto C De OliveiraRobert B Love
Sep 24, 2010·Transplantation·Maarten G J SnoeijsL W Ernest van Heurn
Oct 28, 2010·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·A K MathurR M Merion
Mar 26, 2011·The New England Journal of Medicine·D James CooperUNKNOWN Australian and New Zealand Intensive Care Society Clinical Trials Group

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Citations

Mar 15, 2018·Transplantation Direct·Janske ReilingJonathan Fawcett
Jan 4, 2020·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Kimia HonarmandIan M Ball
Jan 4, 2020·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Kimia HonarmandIan M Ball
Feb 5, 2013·The Medical Journal of Australia·Raj KumarJohn F Fraser

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