PMID: 8971887Dec 1, 1996Paper

Donor age and graft function

Pediatric Nephrology : Journal of the International Pediatric Nephrology Association
S GellertG May

Abstract

We evaluated survival and renal function of cadaveric donor grafts according to donor age. The median age of the pediatric donors was 7.0 (0.7-16) years in 46 patients [median age 11.8 years (range) 3-16.8 years]. The median age of the adult donors was 34.4 (19-54) years in 59 patients [median age 12.1 years (range) 7-17.3 years]. Thirty patients were treated with azathioprine and prednisolone and 75 with cyclosporine A and prednisolone. The glomerular filtration rate (GFR) and the effective renal plasma flow (ERPF) were determined by the clearances of 51chromium-EDTA and 125iodine-hippurate 1-48 months after kidney transplantation. There was no difference in graft survival between pediatric and adult grafts. There were also no differences in GFR in patients receiving grafts from pediatric or adult donors; 2-3 months after transplantation the GFR in recipients of pediatric grafts was 62 +/- 20 ml/min per 1.73 m2 compared with 61 +/- 21 in those receiving adult grafts. The ERPF in recipients of adult grafts was significantly higher in the 1st month after transplantation: 486 +/- 239 versus 362 +/- 158 ml/min per 1.73 m2. From the 4th to the 6th month after transplantation this difference disappeared: the ERPF of grafts from pedi...Continue Reading

Citations

Nov 8, 2012·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Lars PapeAntonia Zapf
Apr 30, 1999·Transplantation·E QvistC Holmberg
Jun 24, 2005·Transplantation·Luciana de Santis FeltranAlvaro Pacheco-Silva
Aug 10, 2000·Transplant International : Official Journal of the European Society for Organ Transplantation·G FillerI Mai
Oct 15, 2013·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Luciana de Santis FeltranAlvaro Pacheco-Silva
Apr 2, 2014·Journal of Transplantation·J Donati-BourneR A Coleman
Mar 25, 2014·Transplantation Proceedings·S H LeeS I Kim
Aug 30, 2007·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·M NaesensM Sarwal
Nov 3, 2007·Pediatric Transplantation·Visnja LezaicLjubica Djukanovic
Jun 15, 2012·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·M NaesensUNKNOWN SNS01-NIH-CCTPT Multicenter Trial
Oct 13, 2006·Current Opinion in Urology·R J Taylor, D Murillo
Jul 25, 2006·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·L PapeG Offner

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