Donors after cardiac death: validation of identification criteria (DVIC) study for predictors of rapid death

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
M A DeVitaE Chaitin

Abstract

Donation after cardiac death (DCD) is uncommon in part because clinicians cannot prospectively identify patients who are likely to die within 60 min of withdrawal of life-sustaining treatments (LST). UNOS criteria exist but have not been validated. Consecutive patients electively withdrawn from LST at five university-affiliated hospitals were prospectively enrolled. Demographic and treatment characteristics were collected. Chi-square was used to determine risk for death within 60 min and validate the UNOS criteria. A total of 533 patients were enrolled. A total of 28 were excluded from this report due to age <18 years or failure to include time of death. Of 505 (95%) patients, 227 (45%) died within 60 min, 134 (27%) in 1-6 h and 144 (29%) >6 h after withdrawal of LST. A total of 29%, 52%, 65% and 82% of patients with 0,1,2 and 3 UNOS DCD criteria, respectively, died within 60 min of withdrawal of LST. The data validate the UNOS criteria. Patients with no criteria might be excluded from consideration for DCD. Those with more than one criterion are reasonable candidates, while those with a single criterion should be considered if a 50% failure rate for DCD is acceptable.

References

Jan 27, 1995·Transplantation·A CasavillaT Starzl
Apr 15, 1997·Transplantation·G Kootstra
Sep 8, 2001·Critical Care Medicine·UNKNOWN Ethics Committee, American College of Critical Care Medicine, UNKNOWN Society of Critical Care Medicine
Mar 1, 1995·Kennedy Institute of Ethics Journal·Michael A DeVitaCheryl Graziano
Feb 28, 2002·Lancet·Shawn D St PeterPeter J Friend
Feb 10, 2004·Progress in Transplantation : Official Publication, North American Transplant Coordinators Organization ... [et Al.]·Jonathan LewisAnthony D'Alessandro
Aug 17, 2004·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Jeffrey T CooperAnthony M D'Alessandro
Oct 26, 2005·Annals of Surgery·David P FoleyAnthony M D'Alessandro
Jan 24, 2006·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·J L BernatF L Delmonico

❮ Previous
Next ❯

Citations

May 24, 2012·Current Neurology and Neuroscience Reports·Anna J DareJohn F Fraser
Nov 10, 2011·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Paul M ShoreLisa Thompson
Jul 7, 2012·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Patricia S Fontela, Sam D Shemie
Dec 4, 2010·Transplantation·Jennifer E FugateEelco F M Wijdicks
Sep 13, 2012·World Journal of Gastroenterology : WJG·Hieu Le DinhOlivier Detry
Jan 7, 2014·Annales Françaises D'anesthèsie Et De Rèanimation·C AntoineUNKNOWN Steering committee on DCD program
Jan 11, 2014·Annales Françaises D'anesthèsie Et De Rèanimation·L PuybassetUNKNOWN Sfar (Comité d’éthique ICARE)
Aug 6, 2014·Intensive Care Medicine·Olivier LesieurUNKNOWN EPILAT Study Group
Feb 5, 2016·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·J J MooneyG S Dhillon
Jun 30, 2012·AORN Journal·Charles C ReedDarla Mullins
Apr 3, 2012·Annales Françaises D'anesthèsie Et De Rèanimation·L PuybassetUNKNOWN Sfar (Comité d'Éthique ICARE)
Aug 18, 2009·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·C SuntharalingamC J E Watson
Sep 29, 2012·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·D DavilaN Heaton
Mar 27, 2015·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·X HeZ Guo
May 7, 2015·Intensive Care Medicine·Laveena MunshiJason Shahin
Jul 26, 2011·Journal of Hepatology·Diethard MonbaliuDavid Talbot
May 28, 2014·Australian Critical Care : Official Journal of the Confederation of Australian Critical Care Nurses·Nicole L Coleman, Ann Bonner
Nov 29, 2014·Thoracic Surgery Clinics·Haytham ElgharablyDavid P Mason
Oct 27, 2015·Transplant International : Official Journal of the European Society for Organ Transplantation·Paul MurphyWim de Jongh
Aug 9, 2016·Current Neurology and Neuroscience Reports·Carolina B Maciel, David M Greer
Jan 4, 2012·British Journal of Anaesthesia·A R ManaraG O'Callaghan
Feb 26, 2016·Journal of Intensive Care Medicine·Anne L Dalle Ave, David M Shaw
Feb 15, 2015·Journal of Intensive Care Medicine·Amanda van BeinumSonny Dhanani
Jul 24, 2008·Journal of Intensive Care Medicine·Mohamed Y RadyJoan McGregor
Oct 6, 2017·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·A M M KotsopoulosW F Abdo
Jun 27, 2012·Nature Reviews. Neurology·Matthew R Hallman, Michael J Souter
May 2, 2013·Current Opinion in Anaesthesiology·Arne NeyrinckDiethard Monbaliu
May 16, 2015·Critical Care Medicine·Robert M KotloffUNKNOWN Society of Critical Care Medicine/American College of Chest Physicians/Association of Organ Procurement Organizations Donor
Nov 26, 2010·Anesthesia and Analgesia·Adejare Windokun
Jun 30, 2015·Critical Care Medicine·Amanda van BeinumSonny Dhanani
Feb 22, 2013·Current Opinion in Organ Transplantation·J A BradleyC J Watson
Dec 15, 2015·Annals of Surgery·Thomas K GallagherMichael M Abecassis
Aug 18, 2020·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Francisco Santos DiasRoberto Roncon-Albuquerque
Feb 23, 2019·Journal of the Intensive Care Society·Colin GilhooleyPatrick Davies
Mar 12, 2021·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Shin TanakaDavid Gómez- de-Antonio
Mar 17, 2021·Transplant International : Official Journal of the European Society for Organ Transplantation·Shuji OkaharaBronwyn Levvey

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
C SuntharalingamChristopher J Watson
American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
D J ReichASTS Standards on Organ Transplantation Committee
© 2021 Meta ULC. All rights reserved