Dopa responsive insomnia: a forme fruste or precursor of restless legs syndrome?

Journal of the Neurological Sciences
Sanjay Prakash

Abstract

Restless leg syndrome (RLS) is a movement disorder that has a profound impact on sleep, and sleep disturbances are considered as the primary morbidity for seeking treatment in most patients. However, isolated sleep has not been described as a symptom of RLS. Low dose dopaminergic agonists are considered for the treatment in patients with RLS. Herein, we describe 7 patients with isolated insomnia in whom insomnia responded to low dose levo-dopa. Six of them had a family history of RLS. We discuss a possibility of RLS in these patients and suggest to take a trial of l-dopa in patients with isolated insomnia who has a positive family history of RLS or in a patient who do not show response to usual therapies for RLS.

References

May 18, 2006·Movement Disorders : Official Journal of the Movement Disorder Society·Karin Stiasny-KolsterWolfgang H Oertel
Nov 17, 2007·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·V E PearsonC J Earley
Feb 29, 2008·The Journal of Neuropsychiatry and Clinical Neurosciences·Hochang B LeeConstantine G Lyketsos
Feb 4, 2010·Parkinsonism & Related Disorders·K Ray Chaudhuri, Kartik Logishetty
Dec 15, 2010·Frontiers in Neuroanatomy·Ramalingam VetrivelanJun Lu

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Citations

Mar 12, 2015·Journal of the Neurological Sciences·Philippe Huot

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