PMID: 6401844Jan 20, 1983Paper

Dopamine modulates S-potential amplitude and dye-coupling between external horizontal cells in carp retina

Nature
T TeranishiS Kato

Abstract

Horizontal cells in the fish retina are electrically coupled and possess gap junctions so that intracellularly injected dye normally diffuses freely to neighbouring cells. Applied dopamine (DA) alters the spatial properties of the horizontal cell responses to light, increasing the amplitude of photopic L-type S-potentials but decreasing their lateral spread. These effects have been attributed to the action of DA on horizontal cell membrane resistance, particularly at the gap junctions, and our present study on the carp retina agrees with this in showing that DA also restricts intracellular Lucifer yellow (LY) to single injected horizontal cells, an effect, like those of DA on the S-potentials, which is antagonized by the dopamine blocker haloperidol. In addition, we present evidence that dopaminergic interplexiform cells in fish normally function to regulate the spatial properties of responses in horizontal cells, possibly acting on their junctional resistance via a DA-receptor-mediated mechanism. Previous destruction of the interplexiform cells with 6-hydroxydopamine (6-OHDA) resulted in much reduced L-type S-potentials to centred lights but wider lateral spread of these responses, while the dye injected spread extensively to ...Continue Reading

References

Jan 1, 1979·Journal of Neuroscience Research·K Negishi, B D Drujan
Jan 1, 1975·Biochemical Pharmacology·C Sachs, G Jonsson
Feb 15, 1975·The Journal of Comparative Neurology·W K Stell
Mar 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·J H Brown, M H Makman
Feb 1, 1971·The Journal of Physiology·A Kaneko
Sep 1, 1967·The Journal of Physiology·K I Naka, W A Rushton
Jan 1, 1981·Vision Research·M LauferB D Drujan
Jun 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·M PiccolinoH M Gerschenfeld
Mar 1, 1982·Experimental Eye Research·T TeranishiK Negishi

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Citations

Jun 15, 1996·Journal of Neuroscience Research·M LauferR Salas
Sep 1, 1990·Documenta Ophthalmologica. Advances in Ophthalmology·N WiolandN Bonaventure
Mar 1, 1991·Journal of Neurocytology·M Schütte, P Witkovsky
Jun 1, 1996·Molecular Neurobiology·B Rörig, B Sutor
Sep 24, 1999·Molecular Neurobiology·J Nguyen-LegrosP Vernier
Dec 23, 1985·Brain Research·D R O'Brien, J E Dowling
Sep 10, 1984·Life Sciences·M Hadjiconstantinou, N H Neff
Dec 3, 1984·Life Sciences·J C Stoof, J W Kebabian
Jan 1, 1983·Vision Research·G L FainS Callery
Jan 1, 1989·Vision Research·C J Dong, J S McReynolds
Jun 1, 1992·Vision Research·M J LankheetW A van de Grind
Jul 1, 1993·Vision Research·H J Wagner, U D Behrens
Jan 1, 1986·Progress in Biophysics and Molecular Biology·F Ramón, A Rivera
Jan 1, 1995·Neuroscience and Biobehavioral Reviews·E A Kiyatkin
Feb 1, 1992·Neurochemistry International·M B Djamgoz, H J Wagner
Jan 1, 1987·Progress in Neurobiology·S C Massey, D A Redburn
Sep 28, 1984·Neuroscience Letters·T TeranishiS Kato
Sep 7, 1984·Neuroscience Letters·K NegishiS Kato
Jan 7, 1985·Neuroscience Letters·T TeranishiS Kato
Jul 17, 1990·Neuroscience Letters·K Negishi, T Teranishi

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