PMID: 3763052Sep 12, 1986Paper

Dopamine receptors are located on rods in bovine retina

Neuroscience Letters
M R Brann, W S Young

Abstract

In purified rod outer segments, the dopamine receptor antagonist [3H] spiperone and agonist [3H]N-propyl-norapomorphine densely label sites with the pharmacological profile of dopamine-D2 receptors. In cryostat sections of retina, the region with the highest density of specific labeling by both [3H]spiperone and L-(--)-[N-propyl-3H(N)]propylnorapomorphine is the photoreceptor layer (rod inner and outer segments). These data show that dopamine receptors are primarily associated with photoreceptor rods and provide support for recent evidence which suggests that these receptors modulate photoreceptor function.

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Citations

Aug 1, 1990·Documenta Ophthalmologica. Advances in Ophthalmology·M Perossini, P Fornaro
Oct 1, 1991·Cellular and Molecular Neurobiology·A DearryM G Caron
Dec 1, 1992·Metabolic Brain Disease·F A de Azeredo, M F Ribeiro
Sep 24, 1999·Molecular Neurobiology·J Nguyen-LegrosP Vernier
Jul 1, 1993·Vision Research·H J Wagner, U D Behrens
Mar 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·D M WeinerM R Brann
Oct 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·K Harsanyi, S C Mangel
Dec 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·A I CohenK L O'Malley
Apr 15, 2014·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·E Popova
Mar 1, 1990·Journal of Neurochemistry·Z L RossettiM Hadjiconstantinou
Jun 9, 2012·The Journal of Comparative Neurology·Genki OgataAndrew T Ishida
May 1, 1996·Visual Neuroscience·I G Morgan, M K Boelen
Apr 29, 1998·The Journal of Biological Chemistry·I P UdovichenkoD S Williams
May 8, 1993·The Journal of Comparative Neurology·Z Muresan, J C Besharse
May 22, 1993·The Journal of Comparative Neurology·H J WagnerW K Stell
Nov 1, 1989·The Journal of Comparative Neurology·C SavyJ Nguyen-Legros

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