PMID: 36821Jul 1, 1979

Dopamine treatment of spinal hypotension decreases uterine blood flow in the pregnant ewe

S H RolbinR G Wright


In seven pregnant ewes, 3--5 min of hypotension resulting from spinal anesthesia decreased uterine blood flow 17 per cent. Dopamine, in doses sufficient to maintain blood pressure at control values (20--40 micrgram/kg/min) for 3--5 min, further decreased uterine blood flow to 56 per cent less than control and increased uterine vascular resistance to 50 per cent more than control. Following 30 min of hypotension, 30 min of dopamine administration in doses sufficient to restore blood pressure to control values (5--20 microgram/kg/min) similarly decreased uterine blood flow to 29 per cent less than control and increased uterine vascular resistance to 35 per cent more than control.


Jan 1, 1983·Archives of Gynecology·W Grünberger, S Szalay
May 1, 1994·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·P Morgan
Apr 21, 1981·Journal of Theoretical Biology·C B Harley
Feb 1, 1992·Trends in Ecology & Evolution·A KacelnikC Bernstein
Jul 1, 1994·Trends in Ecology & Evolution·S H Orzack, E Sober
Dec 14, 2011·International Journal of Obstetric Anesthesia·N TimezguidJ-L Pallot
Apr 1, 1991·Mayo Clinic Proceedings·R A StricklandG K Danielson
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Jan 1, 1992·American Journal of Obstetrics and Gynecology·A C SantosM Finster
Sep 25, 2004·Critical Care Clinics·Jeanne S Sheffield

Related Concepts

Vascular Resistance
Diastolic Blood Pressure
Dall Sheep
Blood Flow
Pulmonary Vascular Resistance
Stroke Volume
Dopamine Measurement
Absence of Sensation

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