Dopaminergic innervation and modulation of hippocampal networks

Cell and Tissue Research
Elke Edelmann, Volkmar Lessmann

Abstract

The catecholamine dopamine plays an important role in hippocampus-dependent plasticity and related learning and memory processes. Dopamine secretion in the hippocampus is activated by, e.g., salient or novel stimuli, thereby helping to establish and to stabilize hippocampus-dependent memories. Disturbed dopaminergic function in the hippocampus leads to severe pathophysiological conditions. While the role and importance of dopaminergic modulation of hippocampal networks have been unequivocally proven, there is still a lack of detailed molecular and cellular mechanistic understanding of how dopamine orchestrates these hippocampal processes. In this chapter of the special issue "Hippocampal structure and function," we will discuss the current understanding of dopaminergic modulation of basal synaptic transmission and long-lasting, activity-dependent potentiation or depression.

References

Aug 8, 1990·The Journal of Comparative Neurology·Y SamsonJ N Davis
May 1, 1987·Brain Research·R D Oades, G M Halliday
Jun 1, 1980·Neuroscience Letters·B ScattonS Bischoff
Jan 28, 1982·Brain Research·K IshikawaJ L McGaugh
Mar 28, 1995·Proceedings of the National Academy of Sciences of the United States of America·Y Y Huang, E R Kandel
Jan 1, 1996·Annual Review of Neuroscience·M F Bear, W C Abraham
Jan 1, 1996·Hippocampus·J J Wagner, B E Alger
Jan 1, 1997·Progress in Neuro-psychopharmacology & Biological Psychiatry·A GasbarriM G Packard
Apr 1, 1997·Brain Research. Molecular Brain Research·M C DefagotM C Antonelli
Jan 24, 1998·European Journal of Pharmacology·S SigalaP Spano
Jan 14, 1998·Neuroreport·F I TaraziR J Baldessarini
Apr 18, 1998·International Clinical Psychopharmacology·P Willner
May 28, 1998·Current Biology : CB·E P Huang
Jan 23, 1999·Journal of Neurophysiology·D A Hoffman, D Johnston
Jul 8, 1999·Current Opinion in Neurobiology·D JohnstonJ C Magee
Dec 14, 1999·Learning & Memory·J D Sweatt
Jun 9, 2000·Annual Review of Neuroscience·S J MartinR G Morris
Oct 19, 2000·Neuroscience·Z U KhanA de la Calle
Apr 3, 2001·Annual Review of Neuroscience·G Bi, M Poo
Oct 9, 2001·Mechanisms of Ageing and Development·F AmentaS K Tayebati

❮ Previous
Next ❯

Citations

Aug 24, 2019·Brain Structure & Function·Jonas A HospM Reisert
Nov 5, 2019·Frontiers in Synaptic Neuroscience·Valentyna Dubovyk, Denise Manahan-Vaughan
Mar 16, 2019·Frontiers in Neuroscience·Jelena CiricJasna Saponjic
Aug 22, 2018·Cell and Tissue Research·Oliver von Bohlen Und HalbachJon Storm-Mathisen
Nov 24, 2020·Acta Neuropathologica Communications·Lin LinDax A Hoffman
Dec 10, 2020·Scientific Reports·Valentin BaumannKerstin Krauel

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.