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Dopaminergic neurotransmission dysfunction induced by amyloid-β transforms cortical long-term potentiation into long-term depression and produces memory impairment

Neurobiology of Aging

Apr 23, 2016

Perla Moreno-CastillaF Bermúdez-Rattoni

Abstract

Alzheimer's disease (AD) is a neurodegenerative condition manifested by synaptic dysfunction and memory loss, but the mechanisms underlying synaptic failure are not entirely understood. Although dopamine is a key modulator of synaptic plasticity, dopaminergic neurotransmission dysfuncti...read more

Mentioned in this Paper

Neuro-Oncological Ventral Antigen 2
Buffers
Familial Alzheimer Disease (FAD)
In Vivo
Biochemical Pathway
Memory Loss
Tissue Membrane
Adrenal Cortex Diseases
Physiologic Pulse
Amnesia
4
57
Paper Details
References
  • References48
  • Citations7
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Dopaminergic neurotransmission dysfunction induced by amyloid-β transforms cortical long-term potentiation into long-term depression and produces memory impairment

Neurobiology of Aging

Apr 23, 2016

Perla Moreno-CastillaF Bermúdez-Rattoni

PMID: 27103531

DOI: 10.1016/j.neurobiolaging.2016.02.021

Abstract

Alzheimer's disease (AD) is a neurodegenerative condition manifested by synaptic dysfunction and memory loss, but the mechanisms underlying synaptic failure are not entirely understood. Although dopamine is a key modulator of synaptic plasticity, dopaminergic neurotransmission dysfuncti...read more

Mentioned in this Paper

Neuro-Oncological Ventral Antigen 2
Buffers
Familial Alzheimer Disease (FAD)
In Vivo
Biochemical Pathway
Memory Loss
Tissue Membrane
Adrenal Cortex Diseases
Physiologic Pulse
Amnesia
4
57

Similar Papers Found In These Feeds

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Paper Details
References
  • References48
  • Citations7
12345
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