PMID: 9646067Jul 1, 1998Paper

Doppler echocardiographic assessment of left ventricular isovolemic relaxation flow

Giornale italiano di cardiologia
A Capezzuto, D Pontillo

Abstract

It is not infrequent to observe a peculiar intraventricular relaxation flow (IRF) pattern during the isovolumic relaxation time (IRT), especially in patients (pts) with left ventricular hypertrophy (LVH). This is even more likely in pts with hypertrophic obstructive cardiomyopathy and in VVI-paced pts. Despite these observations, the prevalence and clinical relevance of this finding have not been evaluated thoroughly and systematically in a consecutive series of patients. Ninety-two consecutive pts underwent a conventional Doppler echo study for the evaluation of systolic and diastolic function (fractional shortening, EF, E and A wave velocity, duration and ratio, and IRT). of these, 42 pts had LVH, 14 had mitral regurgitation (MR) with depressed EF, 8 had CAD with depressed EF and 28 were normal subjects. IF was searched for during the evaluation of IRT and its duration, velocity and integral were measured when noted. Fifty-six patients (61%) showed an IRF at Doppler examination. Of these, fifteen were normal subjects (53%) and 34 (81%, p = 0.03 vs normal) were hypertensive pts. Among pts with depressed EF, only two of 14 with MR and 5 of 8 with no MR showed an IRF (14 vs 62%; p = 0.032). When evaluating LV function, we observ...Continue Reading

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