Abstract
Noninvasive assessment of pulmonary vascular resistance has not been well defined. Cardiac catheterization findings in 33 patients with congenital heart disease (mean age 1.4 years) were compared with Doppler echocardiographic parameters. The right ventricular pre-ejection period (RVPEP), ejection time (RVET), and the ration RVPEP/RVET correlated better with pulmonary vascular resistance than with pulmonary artery pressure. A highly significant correlation with a small standard error of estimate (SEE) was demonstrated between pulmonary vascular resistance and a newly derived parameter RVPEP/velocity time integral (VTI) [r = 0.87, p < 0.0001, SEE = 2]. An RVPEP/VTI value of < 0.4 seconds/meter (M) was able to select patients with pulmonary vascular resistance < 3 Wood Unit.M2, even in the presence of pulmonary artery hypertension caused by increased pulmonary blood flow, with 97% accuracy (100% sensitivity, and 92% specificity). An RVPEP/VTI value of 0.4 to 0.6 seconds/M identified patients with pulmonary vascular resistance between 3 to 7.5 Wood Unit.M2 with 91% accuracy, and a value of > or = 0.6 seconds/ M selected patients with total pulmonary vascular resistance > or = 7.5 Wood Unit.M2 with 94% accuracy.
References
May 1, 1978·Circulation·T RiggsJ Liebman
Nov 1, 1978·The American Journal of Cardiology·E W SpoonerJ M Sigmann
Mar 4, 1976·The American Journal of Cardiology·J AskenaziS Treves
Oct 1, 1975·Circulation·S HirschfeldS Kaplan
May 1, 1989·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·J G Stevenson
May 1, 1989·The Journal of Pediatrics·T Zellers, H P Gutgesell
Aug 1, 1988·Journal of the American College of Cardiology·M J CooperN H Silverman
Mar 1, 1987·Journal of the American College of Cardiology·K L ChanA J Tajik
Sep 15, 1987·The American Journal of Cardiology·B O Kristensen, S J Goldberg
Aug 1, 1986·The American Journal of Cardiology·D M FriedmanR Barst
Mar 1, 1987·The American Journal of Cardiology·A DabestaniW L Henry
Apr 1, 1986·Journal of the American College of Cardiology·G R MarxS J Goldberg
Apr 1, 1986·The American Journal of Cardiology·R Martin-DuranF Nistal
Oct 1, 1985·Journal of the American College of Cardiology·P J CurrieA J Tajik
Oct 1, 1984·Circulation·P G Yock, R L Popp
Nov 1, 1984·Journal of the American College of Cardiology·J G StevensonW G Guntheroth
Apr 1, 1984·The American Journal of Cardiology·D KosturakisC Loeber
Dec 1, 1982·The American Journal of Cardiology·S J GoldbergY Carnahan
Aug 1, 1983·Circulation·A KitabatakeH Abe
Jun 1, 1980·Circulation·N H SilvermanA M Rudolph
Nov 1, 1992·Clinical Cardiology·M M MirrakhimovM L Zlatkovsky
Citations
Aug 10, 2010·Pediatric Cardiology·Gehan AttiaAsser Elsharkawy
Oct 12, 2012·Pediatric Cardiology·Ayhan CevikCihat Sanli
Mar 26, 2003·Journal of the American College of Cardiology·Amr E AbbasSteven J Lester
Apr 1, 2011·European Heart Journal·Annelies E van der HulstEduard R Holman
Feb 15, 2001·Echocardiography·Thomas G. Di SessaBruce S. Alpert
Jun 10, 2010·Cardiovascular Ultrasound·Vincent RouleEric Saloux
Mar 24, 2009·Paediatric Drugs·Robert Tulloh
Sep 9, 1999·Radiology·E MousseauxJ C Gaux
Mar 3, 2007·Radiology·Javier SanzMichael Poon
Jan 7, 2014·The American Journal of Cardiology·Brad Robinson, Makram Ebeid
Feb 4, 2012·Echocardiography·Dheeraj Deo BhattRajiv Mahajan
Sep 15, 2009·International Journal of Cardiology·Hiroto UtsunomiyaMasafumi Kitakaze
Sep 20, 2016·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Philip T LevyGautam K Singh
Mar 2, 2018·Heart and Vessels·Yumi ShiinaMichinobu Nagao
Mar 23, 2002·International Anesthesiology Clinics·Andrew MaslowScott Mackinnon
May 24, 2006·Expert Review of Cardiovascular Therapy·Robert Tulloh
Aug 2, 2005·American Journal of Physiology. Heart and Circulatory Physiology·Julien BoissiereVeronique Eder
May 14, 2016·Current Treatment Options in Cardiovascular Medicine·J Sawalla Guseh