Doppler echocardiographic evaluation of pulmonary vascular resistance in children with congenital heart disease

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
M R EbeidH Gebland

Abstract

Noninvasive assessment of pulmonary vascular resistance has not been well defined. Cardiac catheterization findings in 33 patients with congenital heart disease (mean age 1.4 years) were compared with Doppler echocardiographic parameters. The right ventricular pre-ejection period (RVPEP), ejection time (RVET), and the ration RVPEP/RVET correlated better with pulmonary vascular resistance than with pulmonary artery pressure. A highly significant correlation with a small standard error of estimate (SEE) was demonstrated between pulmonary vascular resistance and a newly derived parameter RVPEP/velocity time integral (VTI) [r = 0.87, p < 0.0001, SEE = 2]. An RVPEP/VTI value of < 0.4 seconds/meter (M) was able to select patients with pulmonary vascular resistance < 3 Wood Unit.M2, even in the presence of pulmonary artery hypertension caused by increased pulmonary blood flow, with 97% accuracy (100% sensitivity, and 92% specificity). An RVPEP/VTI value of 0.4 to 0.6 seconds/M identified patients with pulmonary vascular resistance between 3 to 7.5 Wood Unit.M2 with 91% accuracy, and a value of > or = 0.6 seconds/ M selected patients with total pulmonary vascular resistance > or = 7.5 Wood Unit.M2 with 94% accuracy.

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Citations

Mar 26, 2003·Journal of the American College of Cardiology·Amr E AbbasSteven J Lester
Apr 1, 2011·European Heart Journal·Annelies E van der HulstEduard R Holman
Feb 15, 2001·Echocardiography·Thomas G. Di SessaBruce S. Alpert
Jun 10, 2010·Cardiovascular Ultrasound·Vincent RouleEric Saloux
Jan 7, 2014·The American Journal of Cardiology·Brad Robinson, Makram Ebeid
Sep 20, 2016·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Philip T LevyGautam K Singh
Mar 23, 2002·International Anesthesiology Clinics·Andrew MaslowScott Mackinnon
May 24, 2006·Expert Review of Cardiovascular Therapy·Robert Tulloh
Aug 2, 2005·American Journal of Physiology. Heart and Circulatory Physiology·Julien BoissiereVeronique Eder
May 14, 2016·Current Treatment Options in Cardiovascular Medicine·J Sawalla Guseh

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