PMID: 9438222Jan 23, 1998Paper

Doppler echocardiographic reference values for healthy rhesus monkeys under ketamine hydrochloride sedation

Journal of Medical Primatology
C E KorcarzR M Lang

Abstract

Cardiac ultrasound is a noninvasive technique that is commonly used to serially evaluate cardiac structure and function. Recent advances in Doppler-Echocardiography enable the ultrasonographer to perform a sophisticated noninvasive assessment of cardiovascular physiology. The Rhesus monkey is a frequently used non-human primate animal model of human cardiovascular disease because this species closely models human anatomy and physiology. However, while this species is frequently used in cardiovascular research, standardized echocardiographic values generated from large numbers of normal Rhesus are not available. In the present study, we performed cardiac ultrasound imaging on 28 healthy Rhesus monkeys to obtain normal reference values of cardiovascular structure and function in this species. Nomograms were generated from these data by plotting parameters of cardiovascular geometry and function with body weight. These normal reference data were compared to previously reported values obtained from prior studies that used noninvasive, invasive, and morphometric techniques.

References

Feb 11, 1991·Anesthesia and Analgesia·N A NussmeierT H Stanley
Aug 1, 1963·Circulation Research·H SANDLER, H T DODGE

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Citations

Nov 26, 2008·Doklady Biological Sciences : Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections·M P RoshchevskyI M Roshchevskaya
Mar 14, 2009·Journal of Biomedicine & Biotechnology·Jason LazarLouis Salciccioli
Dec 19, 2014·Frontiers in Pediatrics·Patrick A RossChristopher J L Newth
Aug 31, 2016·Journal of Veterinary Internal Medicine·J HäggströmI Ljungvall
Mar 13, 2008·Journal of Medical Primatology·Huo-Ling TangSong Li
Mar 17, 2020·Experimental Animals·Shunya NakayamaNaohide Ageyama
Jun 29, 2007·Drugs in R&D·Gilles Hanton
Oct 20, 2017·Journal of Medical Primatology·Murilo Gomes de Soutello CharlierLuiz Carlos Vulcano
May 12, 2018·Journal of Veterinary Internal Medicine·Elodie DarnisKris Gommeren
Sep 7, 2004·Journal of the American Animal Hospital Association·Rosemary A HenikHattie B Bortnowski
Jun 22, 2021·Frontiers in Veterinary Science·Yu UedaJoshua A Stern

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