Doppler sonography: a noninvasive method for evaluation of hepatic venocclusive disease

AJR. American Journal of Roentgenology
B P BrownR Gingrich

Abstract

Hepatic venocclusive disease is a serious complication associated with chemotherapy and radiation used in bone marrow transplantation patients. In the past, liver biopsy has been the only reliable means of diagnosing venocclusive disease. Biopsy in such patients may be dangerous or impossible because of severe coagulopathies. The purpose of our study was to evaluate duplex Doppler sonography in diagnosing hepatic venocclusive disease. We measured the blood velocity and flow in the portal vein, hepatic vein, and inferior vena cava of six patients who were histologically proved to have developed hepatic venocclusive disease after bone marrow transplantation. There were three men and three women with a mean age of 32 years (range, 21-44 years). Examination with Doppler sonography suggested the diagnosis a mean of 41 days (range, 11-62 days) after transplantation. In three patients, the diagnosis was suggested by reversed or "to and fro" flow in the portal vein. In the other three patients, the diagnosis was suggested by a decreased flow in the portal vein. One of these patients with decreased flow had subclinical hepatic venocclusive disease. In this patient, it was not the absolute level of flow but the decrease from a baseline e...Continue Reading

Citations

May 31, 2001·British Journal of Haematology·C LiatsosA K Burroughs
May 2, 2002·Journal of Hematotherapy & Stem Cell Research·Sally AraiGeorgia B Vogelsang
Jul 23, 2002·Transplantation·Nathalie LassauOlivier Hartmann
Feb 22, 2008·Journal of Gastroenterology and Hepatology·Prabhleen ChahalKeith D Lindor
Nov 21, 2009·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Meir H ScheinfeldMordecai Koenigsberg
Nov 1, 1992·The British Journal of Radiology·R KishimotoG Irie
Nov 1, 1992·The British Journal of Radiology·W Kincaid, R Edwards
Oct 11, 2014·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Kasiani C MyersSonata Jodele
Oct 10, 2013·British Journal of Haematology·Fiona L DignanUNKNOWN British Society for Blood and Marrow Transplantation
Feb 1, 1995·Seminars in Ultrasound, CT, and MR·D G Mitchell, L N Nazarian
Jun 1, 1997·Pediatric Clinics of North America·E C Benya, S Goldman
Apr 6, 2002·Clinics in Liver Disease·Pablo R Ros, Koenraad J Mortele
May 18, 2001·Best Practice & Research. Clinical Gastroenterology·M J Gebel, S Göhde
Nov 19, 2015·Case Reports in Obstetrics and Gynecology·Nikolaos TsagkasTheodor Stefos
Feb 1, 1995·Seminars in Ultrasound, CT, and MR·W J Zwiebel
Mar 1, 1993·Blood Reviews·E CarrerasC Rozman
Oct 18, 2003·Current Opinion in Hematology·Martha WadleighPaul Richardson
Sep 13, 2003·Ultrasound Quarterly·Harriet J Paltiel
Mar 22, 2019·Expert Review of Gastroenterology & Hepatology·Federico RavaioliDavide Festi
Aug 1, 2009·Expert Review of Hematology·Paul RichardsonVincent Ho
Nov 11, 2003·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Eduard GhersinAhuva Engel
Jan 1, 1999·Medizinische Klinik·H H MohrK H Meyer zum Büschenfelde
Mar 26, 2021·International Journal of Hematology·Mutsumi NishidaTakanori Teshima
Mar 31, 2019·The American Journal of Pathology·Sven GüntherDavid Montani

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