DOPPS estimate of patient life years attributable to modifiable hemodialysis practices in France

Néphrologie & thérapeutique
Bernard CanaudFriedrich K Port

Abstract

In this study, we used a prevalent cross-sectional sample of French hemodialysis patients from Dialysis Outcomes and Practice Patterns Study (DOPPS) 2 (2002-2004) to determine the percentage of patients whose values failed to meet targets in six different areas of hemodialysis practice (dialysis dose, anemia, serum phosphorus (PO(4)), serum calcium (Ca), serum albumin and catheter use for vascular access). Cox survival models, with adjustments for patient characteristics, were used for these analyses to estimate mortality hazard ratios (HR). Based on the mortality HR, the fraction of patients outside each target and the total HD population in France, we estimated the number of patient life years that could potentially be gained if every chronic, in-center hemodialysis patient in France who is currently outside of the specified target was able to achieve it. The proportion of patients failing to meet one of the six practice targets in France varied from 15% (dialysis dose) to 75% (albumin) while the percentage of patients complying with all six targets was restricted to 1.2%. The relative risk of mortality (RR) associated with being outside these targets varied from 1.12 to 1.46. Based on these two measures the life-years surviv...Continue Reading

References

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Feb 8, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Robert A WolfeFriedrich K Port

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Citations

May 28, 2013·BMC Nephrology·Steven GrangéMichel Godin
Oct 7, 2011·Néphrologie & thérapeutique·Hélène BeaussartRaymond Azar
Nov 9, 2012·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Denis FouqueTilman Drüeke

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