Dorsal periaqueductal gray simultaneously modulates ventral subiculum induced-plasticity in the basolateral amygdala and the nucleus accumbens

Frontiers in Behavioral Neuroscience
Omer Horovitz, G Richter-Levin

Abstract

The ventral subiculum of the hippocampus projects both to the basolateral amygdala (BLA), which is typically, associated with a response to aversive stimuli, as well as to the nucleus accumbens (NAcc), which is typically associated with a response to appetitive stimuli. Traditionally, studies of the responses to emotional events focus on either negative or positive affect-related processes, however, emotional experiences often affect both. The ability of high-level processing brain regions (e.g., medial prefrontal cortex) to modulate the balance between negative and positive affect-related regions was examined extensively. In contrast, the ability of low-level processing areas (e.g., periaqueductal gray-PAG) to do so, has not been sufficiently studied. To address whether midbrain structures have the ability to modulate limbic regions, we first examined the ventral subiculum stimulation's (vSub) ability to induce plasticity in the BLA and NAcc simultaneously in rats. Further, dorsal PAG (dPAG) priming ability to differentially modulate vSub stimulation induced plasticity in the BLA and the NAcc was subsequently examined. vSub stimulation resulted in plasticity in both the BLA and the NAcc simultaneously. Moreover, depending on s...Continue Reading

References

Dec 20, 1993·Behavioural Brain Research·F G GraeffR M Oliveira
Dec 20, 1993·Behavioural Brain Research·J E LeDoux
Aug 1, 1995·Progress in Neurobiology·M M Behbehani
Jan 1, 1996·Progress in Brain Research·J LeDoux
Jul 1, 1997·The Journal of Neuropsychiatry and Clinical Neurosciences·M Davis
Jan 7, 1998·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·J E Ledoux, J Muller
May 13, 1999·Brain Research·F A GuarraciB S Kapp
Mar 13, 2001·Molecular Psychiatry·M Davis, P J Whalen
Mar 22, 2001·Nature Reviews. Neuroscience·H van PraagF H Gage
Jan 22, 2002·Neuroscience and Biobehavioral Reviews·R E AdamecA Collins
May 30, 2002·Neuroscience and Biobehavioral Reviews·Rudolf N CardinalBarry J Everitt
Jan 17, 2003·Psychological Review·James A Russell
Aug 13, 2003·The European Journal of Neuroscience·Cláudia M Miranda-PaivaLuciano F Felicio
Sep 30, 2003·Cellular and Molecular Neurobiology·Joseph LeDoux
Dec 8, 2004·Progress in Neurobiology·Marie A Pezze, Joram Feldon
Mar 21, 2006·Trends in Neurosciences·Bernard W Balleine, Simon Killcross
Aug 8, 2006·Annals of the New York Academy of Sciences·Lisa M ShinRoger K Pitman
Oct 25, 2007·Current Biology : CB·Joseph LeDoux
Feb 19, 2008·The European Journal of Neuroscience·Inna Kogan, Gal Richter-Levin
Oct 3, 2008·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Mauricio R DelgadoElizabeth A Phelps
Sep 18, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Herbert E CovingtonEric J Nestler
Mar 20, 2010·Current Opinion in Neurobiology·Sara E Morrison, C Daniel Salzman
May 18, 2010·Nature Neuroscience·Vincent VialouEric J Nestler
Dec 15, 2010·Physiology & Behavior·Esperanza QuinteroJuan Carlos López
Dec 17, 2010·Frontiers in Behavioral Neuroscience·Inna Kogan, Gal Richter-Levin

❮ Previous
Next ❯

Citations

Oct 21, 2016·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Rinki SahaGal Richter-Levin
May 28, 2019·Molecular Neurobiology·Julianna KardosLászló Héja
Jul 25, 2021·Neuroscience Bulletin·Priscila Vázquez-LeónBruno A Marichal-Cancino

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Related Feeds

Amygdala and Midbrain Dopamine

The midbrain dopamine system is widely studied for its involvement in emotional and motivational behavior. Some of these neurons receive information from the amygdala and project throughout the cortex. When the circuit and transmission of dopamine is disrupted symptoms may present. Here is the latest research on the amygdala and midbrain dopamine.

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.