Dorsal posterior parietal rTMS affects voluntary orienting of visuospatial attention

Cerebral Cortex
Gregor ThutA Pascual-Leone

Abstract

Patients with lesions in posterior parietal cortex (PPC) are relatively unimpaired in voluntarily directing visual attention to different spatial locations, while many neuroimaging studies in healthy subjects suggest dorsal PPC involvement in this function. We used an offline repetitive transcranial magnetic stimulation (rTMS) protocol to study this issue further. Ten healthy participants performed a cue-target paradigm. Cues prompted covert orienting of spatial attention under voluntary control to either a left or right visual field position. Targets were flashed subsequently at the cued or uncued location, or bilaterally. Following rTMS over right dorsal PPC, (i) the benefit for target detection at cued versus uncued positions was preserved irrespective of cueing direction (left- or rightward), but (ii) leftward cueing was associated with a global impairment in target detection, at all target locations. This reveals that leftward orienting was still possible after right dorsal PPC stimulation, albeit at an increased overall cost for target detection. In addition, rTMS (iii) impaired left, but (iv) enhanced right target detection after rightward cueing. The finding of a global drop in target detection during leftward orienting...Continue Reading

References

Dec 1, 1989·Journal of Clinical and Experimental Neuropsychology·P W Halligan, J C Marshall
Jan 1, 1987·Neuropsychologia·M I PosnerR D Rafal
Oct 1, 1981·Annals of Neurology·M M Mesulam
Sep 26, 1996·Nature·S HeJ Intriligator
Nov 22, 1997·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·H O Karnath
Jan 28, 1998·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·S PitzalisP Zoccolotti
Mar 14, 1998·Proceedings of the National Academy of Sciences of the United States of America·M Corbetta
Oct 8, 1998·Brain : a Journal of Neurology·N SmaniaC A Marzi
Jan 5, 1999·Brain : a Journal of Neurology·H O KarnathJ Dichgans
Aug 31, 1999·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·A Pascual-LeoneJ P Keenan
Feb 11, 2000·Neurology·M Niemeier, H O Karnath
Mar 4, 2000·Nature Neuroscience·J B HopfingerG R Mangun
May 29, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·W MuellbacherM Hallett
Oct 26, 2000·Brain : a Journal of Neurology·R J Perry, S Zeki
Feb 13, 2001·Neuroscience and Biobehavioral Reviews·B J Losier, R M Klein
Mar 17, 2001·Nature Reviews. Neuroscience·N Kanwisher, E Wojciulik
May 18, 2001·Experimental Brain Research·P BartolomeoS Chokron
Sep 21, 2001·Journal of Cognitive Neuroscience·K A ShapiroA Caramazza
Oct 30, 2001·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·T TougeJ C Rothwell
Nov 2, 2001·Cognitive Psychology·J Intriligator, P Cavanagh
Jan 22, 2002·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Jose Rafael RomeroAlvaro Pascual-Leone
Feb 22, 2002·Neuroscience and Biobehavioral Reviews·Paolo Bartolomeo, Sylvie Chokron
May 8, 2002·Nature Reviews. Neuroscience·Maurizio Corbetta, Gordon L Shulman
Aug 10, 2002·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Babak BoroojerdiRudolf Töpper
Aug 17, 2002·Brain : a Journal of Neurology·Otto BjoertomtVincent Walsh

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Citations

Feb 29, 2008·Journal of Cognitive Neuroscience·Olivier CollignonClaude Veraart
Apr 16, 2009·Journal of Cognitive Neuroscience·Alexandre ZenonEtienne Olivier
May 8, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Paolo CapotostoMaurizio Corbetta
Nov 24, 2012·Cerebral Cortex·Ana B ChicaPaolo Bartolomeo
Dec 24, 2008·Neuroreport·Lotfi B MerabetAlvaro Pascual-Leone
Jul 26, 2012·Neuropharmacology·Martin DreslerDimitris Repantis
Jun 7, 2016·Current Biology : CB·Laura DuguéMarisa Carrasco
Feb 4, 2006·Neuropsychologia·M F S Rushworth, P C J Taylor
Aug 15, 2014·Neurorehabilitation and Neural Repair·Jennifer A SemrauSean P Dukelow
Nov 16, 2017·Social Cognitive and Affective Neuroscience·Manon MulckhuyseKarin Roelofs
Jun 20, 2008·Experimental Brain Research·Yu Jin, Claus C Hilgetag
Nov 11, 2005·Current Opinion in Neurology·A David Milner, Robert D McIntosh
Feb 18, 2016·Experimental Brain Research·Yasaman BagherzadehDimitrios Pantazis
Sep 26, 2014·European Archives of Psychiatry and Clinical Neuroscience·Malek Bajbouj, Frank Padberg
Feb 19, 2020·Translational Psychiatry·Nicholas L BalderstonChristian Grillon
Oct 17, 2008·Journal of Neurophysiology·Ryota KanaiVincent Walsh
Jun 25, 2019·Journal of the Indian Institute of Science·Sanjna BanerjeeDevarajan Sridharan
Jun 28, 2020·Scientific Reports·Carsten GießingChristiane M Thiel

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