Dorsal root entry zone lesioning used to treat central neuropathic pain in patients with traumatic spinal cord injury: a systematic review

Spine
Matthew R DenkersMary E Gauld

Abstract

A systematic review was conducted for studies of any design. To evaluate the effectiveness and safety of dorsal root entry zone lesioning in treating central neuropathic pain of patients with traumatic spinal cord injury. Central neuropathic pain has a great impact on the quality of life of many patients with traumatic spinal cord injury. Dorsal root entry zone lesioning has become one of several treatment options. No previous systematic reviews were found that address this indication for the procedure. Several computerized databases were searched along with reference lists of eligible articles and personal files of advisory panel members. Only primary studies of patients older than 13 years with both traumatic spinal cord injury and central neuropathic pain receiving dorsal root entry zone lesioning were included. Two assessors independently performed data extraction and quality assessment for all the studies. The selection criteria were met by 11 studies. All were case series of 5 to 54 patients. As reported by 10 of the studies, at least 50% of the patients attained more than 50% pain relief or experienced no pain limitation of activity and no need for narcotics. However, all the studies had poorly defined eligibility criter...Continue Reading

References

Jul 1, 1979·Journal of Neurosurgery·B S Nashold, R H Ostdahl
May 1, 1990·Journal of Neurosurgery·R F Young
Jan 1, 1990·British Journal of Neurosurgery·B S NasholdA O el-Naggar
Jan 1, 1989·British Journal of Neurosurgery·C E RawlingsB S Nashold
Oct 1, 1986·Journal of Neurosurgery·A H Friedman, B S Nashold
Jul 1, 1986·The Journal of the American Paraplegia Society·R M Woolsey
Feb 8, 1985·Deutsche medizinische Wochenschrift·H Wiegand, W Winkelmüller
Feb 1, 1973·Paraplegia·D C Burke
Sep 1, 1981·Journal of Neurosurgery·B S Nashold, E Bullitt
Jun 1, 1982·Paraplegia·W H DonovanM Dimitrijevic
Jun 1, 1980·Pain·J S RichardsG Bennett
Jun 1, 1994·Journal of Neurology, Neurosurgery, and Psychiatry·D G Thomas, N D Kitchen
Feb 1, 1993·Journal of Spinal Disorders·R E EdgarA D Obert
Apr 1, 1996·Archives of Physical Medicine and Rehabilitation·D M CairnsM D Scott
Oct 1, 1995·Paraplegia·A G AnkeJ K Stanghelle
Feb 1, 1997·Spinal Cord·P J SiddallM J Cousins
Feb 21, 1998·Spinal Cord·G DemirelN Kesiktaş
Oct 10, 1998·Neurologic Clinics·M M Backonja, B S Galer
Nov 20, 1998·Archives of Physical Medicine and Rehabilitation·N Westgren, R Levi
Jan 19, 1999·Dermatologic Clinics·C M Ridley
Dec 1, 1962·JAMA : the Journal of the American Medical Association·L I KAPLANH A RUSK
Mar 1, 1951·A.M.A. Archives of Neurology and Psychiatry·L J POLLOCKJ R FINKLE
Dec 1, 1946·Annals of Surgery·R H Kennedy
Nov 1, 1947·Journal of Neurosurgery·L DAVIS, J MARTIN
Dec 1, 1946·Annals of Surgery·R H KENNEDY

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Citations

Jul 31, 2013·Neurocritical Care·Axel Petzold, Armand Girbes
Jan 27, 2005·Photomedicine and Laser Surgery
Sep 23, 2014·Neurosurgery Clinics of North America·Peter Konrad
Dec 18, 2010·Neurología : publicación oficial de la Sociedad Española de Neurología·F Ruiz-JuretschkeT Panadero
Oct 3, 2009·PM & R : the Journal of Injury, Function, and Rehabilitation·Diana D Cardenas, Elizabeth R Felix
Feb 21, 2007·Pain Practice : the Official Journal of World Institute of Pain·John D Loeser
Oct 22, 2013·Arquivos de neuro-psiquiatria·Manoel Jacobsen TeixeiraAngelo Daros Cecon

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