PMID: 9639354Jun 25, 1998Paper

Dorsal specification in blastoderm at the blastula stage in the goldfish, Carassius auratus

Development, Growth & Differentiation
Etsuro YamahaF Yamazaki

Abstract

The teleost dorsoventral axis cannot be morphologically distinguished before gastrulation. Previous studies by the current authors have shown that localized dorsalizing activity in the yolk cell (YC) induces the dorsal tissues in the overlying blastoderm. In order to examine whether or not dorsal blastomeres are committed to their dorsal fate before the gastrula stage, a variety of transplant operations were performed in goldfish blastoderms at the mid- to late-blastula stages. When the blastoderm was cut from the YC, rotated horizontally at 180 degrees, and recombined with the YC, the blastoderm frequently developed two axes, indicating that dorsal blastomeres of the blastula had already acquired the ability to differentiate into the organizer in the absence of dorsalizing signals from the YC. This result was further confirmed by experiments using ventralized embryos in which no dorsal structures formed: the axis formation was frequently observed in the normal blastoderm combined with the ventralized YC at the blastula stage. However, the axes formed in the absence of dorsal information from the YC exhibited a lower dorso-anterior index. Furthermore, the dorsal specification was not stably maintained when the dorsal cells were...Continue Reading

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Citations

Feb 8, 2014·PloS One·Taiju SaitoEtsuro Yamaha
Jul 20, 2002·Zoological Science·Satoshi OtaniEtsuro Yamaha
Mar 10, 2016·Wiley Interdisciplinary Reviews. Developmental Biology·Kinya G Ota, Gembu Abe
Jul 4, 2007·Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology·Takafumi FujimotoKatsutoshi Arai
Aug 6, 2013·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Hsin-Yuan TsaiKinya G Ota
Mar 29, 2018·Zygote : the Biology of Gametes and Early Embryos·Dilberto Ribeiro ArashiroJosé Augusto Senhorini

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