Dosage analysis of Z chromosome genes using microarray in silkworm, Bombyx mori

Insect Biochemistry and Molecular Biology
Xingfu ZhaZhonghuai Xiang

Abstract

In many organisms, dosage compensation is needed to equalize sex-chromosome gene expression in males and females. Several genes on silkworm Z chromosome were previously detected to show a higher expression level in males and lacked dosage compensation. Whether silkworm lacks global dosage compensation still remains poorly known. Here, we analyzed male:female (M:F) ratios of expression of chromosome-wide Z-linked genes in the silkworm using microarray data. The expression levels of genes on Z chromosome in each tissue were significantly higher in males compared to females, which indicates no global dosage compensation in silkworm. Interestingly, we also found some genes with no bias (M:F ratio: 0.8-1.2) on the Z chromosome. Comparison of male-biased (M:F ratio more than 1.5) and unbiased genes indicated that the two sets of the genes have functional differences. Analysis of gene expression by sex showed that M:F ratios were, to some extent, associated with their expression levels. These results provide useful clues to further understanding roles of dosage of Z chromosome and some Z-linked sexual differences in silkworms.

References

Jan 1, 1994·Annual Review of Genetics·B S BakerI Marín
Mar 25, 2000·Science·M D AdamsJ C Venter
Feb 13, 2001·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·F OhbayashiT Shimada
Feb 22, 2001·Science·J C VenterX Zhu
May 22, 2001·Archives of Biochemistry and Biophysics·T KusakabeK Koga
Apr 5, 2002·Advances in Genetics·Victoria H Meller, Mitzi I Kuroda
Nov 15, 2002·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Atsuko OtaKatsumi Koga
Apr 26, 2003·Molecular Genetics and Genomics : MGG·Y KoikeT Shimada
Apr 29, 2004·European Journal of Human Genetics : EJHG·Ian W CraigLeonard C Schalkwyk
May 15, 2004·DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes·Kazuei MitaTakuji Sasaki
Dec 14, 2004·Science·Qingyou XiaUNKNOWN Biology Analysis Group
Dec 14, 2004·Nature·UNKNOWN International Chicken Genome Sequencing Consortium
Mar 31, 2005·Trends in Genetics : TIG·James A BirchlerReiner A Veitia
Jun 2, 2005·Insect Molecular Biology·Y MiyagawaT Kusakabe
Jun 21, 2005·Gene Expression Patterns : GEP·Joan S Jorgensen, Liying Gao
Aug 12, 2005·Cytogenetic and Genome Research·H AbeT Shimada
Dec 13, 2005·Nature Genetics·Di Kim Nguyen, Christine M Disteche
Jul 18, 2006·Nucleic Acids Research·Jia YeJun Wang
Dec 19, 2006·Nature Reviews. Genetics·Tobias Straub, Peter B Becker
Jan 24, 2007·Biological Procedures Online·Jeanine S MoreyFrances M Van Dolah
Mar 14, 2007·Journal of Biology·Yuichiro ItohArthur P Arnold
Sep 29, 2007·Genome Biology·Esther Melamed, Arthur P Arnold

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Citations

Apr 27, 2012·Journal of Molecular Evolution·Jun WangMaria D Vibranovski
Aug 13, 2009·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Esther Melamed, Arthur P Arnold
Nov 23, 2011·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Andrea R GschwendRay Ming
Dec 22, 2011·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Ken SaharaWalther Traut
Aug 21, 2013·Trends in Genetics : TIG·Judith E Mank
Nov 26, 2010·Nature Genetics·Yuanyan XiongXionglei He
Mar 7, 2012·Proceedings of the National Academy of Sciences of the United States of America·Eugénie PessiaGabriel A B Marais
Feb 15, 2011·Genome Biology and Evolution·Beatriz Vicoso, Doris Bachtrog
Apr 22, 2011·Genome Biology and Evolution·James R Walters, Thomas J Hardcastle
Oct 26, 2011·Genome Biology and Evolution·Melissa A ToupsMatthew W Hahn
Mar 2, 2012·The Journal of Heredity·Eric T Watson, Jeffery P Demuth
Feb 10, 2012·Molecular Biology and Evolution·James B Pease, Matthew W Hahn
Feb 27, 2010·PLoS Biology·Xinxian Deng, Christine M Disteche
Oct 29, 2013·Annual Review of Entomology·Qingyou XiaQili Feng
Nov 5, 2010·Annual Review of Genetics·Vera B Kaiser, Doris Bachtrog
Oct 4, 2011·Trends in Genetics : TIG·Doris BachtrogNicole Valenzuela
Sep 4, 2015·Molecular Ecology·Jouni KvistIlkka Hanski
Dec 8, 2009·Trends in Genetics : TIG·Sara NaurinDennis Hasselquist
Apr 11, 2009·Trends in Genetics : TIG·Judith E Mank
Sep 10, 2011·International Journal of Evolutionary Biology·Miguel GallachEsther Betrán
Jul 28, 2011·Evolution; International Journal of Organic Evolution·Judith E MankNina Wedell
May 16, 2014·Evolution; International Journal of Organic Evolution·Timothy B SacktonDaniel L Hartl
May 15, 2013·Pest Management Science·Liping GanShiqing Xu
Sep 5, 2015·Genome Biology and Evolution·James R WaltersChris D Jiggins
Oct 14, 2014·Archives of Insect Biochemistry and Physiology·Yanyun WangBin Li
Jan 19, 2017·Annals of the New York Academy of Sciences·Christopher H Chandler
Feb 22, 2014·Genome Biology and Evolution·Gilbert SmithAdriana D Briscoe
Dec 29, 2009·Journal of Molecular Evolution·Libor MořkovskýJiří Hejnar
Sep 29, 2017·Molecular Biology and Evolution·Ann Kathrin HuylmansBeatriz Vicoso

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