PMID: 6975255Nov 1, 1981Paper

Dose--effect relationships, r.b.e. and split-dose effects after gamma-ray and fast neutron irradiation of protoplasts from wild Nicotiana species

International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine
E MagnienM Coppola

Abstract

Protoplasts from a diploid Nicotiana species were used to investigate the effects of gamma-rays and fast neutrons. The damage was assessed by scoring the relative plating efficiencies. The effects of single acute doses, as well as fractionated doses, are described for both qualities of radiation. The dose--r.b.e. relationship, expressing the effectiveness of fast neutrons relative to gamma-rays as a function of dose, appears similar to that of most animal systems, with higher values in the region of lower doses. The fractionation of gamma-ray doses, with sufficiently long time intervals between split doses, allowed a substantial recovery, as known also for X-rays. On the other hand, the fractionation of a fast neutron dose into low single fractions markedly increased the biological effectiveness of the total dose. This could not be explained by cell progression during resting time intervals and necessitated an additional hypothesis, possibly involving other mechanisms in the specific action of low doses of radiation.

References

Dec 12, 1977·Radiation and Environmental Biophysics·H H Rossi
Jan 1, 1969·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·J J Broerse, G W Barendsen

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Citations

Jun 1, 1985·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·E NielsenM Devreux
Feb 1, 1984·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·I NegrutiuM Caboche
Nov 30, 2010·Radiation and Environmental Biophysics·Veronica De MiccoMarco Durante

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