Dose calculation on kV cone beam CT images: an investigation of the Hu-density conversion stability and dose accuracy using the site-specific calibration

Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists
Yi RongBhudatt Paliwal

Abstract

Precise calibration of Hounsfield units (HU) to electron density (HU-density) is essential to dose calculation. On-board kV cone beam computed tomography (CBCT) imaging is used predominantly for patients' positioning, but will potentially be used for dose calculation. The impacts of varying 3 imaging parameters (mAs, source-imager distance [SID], and cone angle) and phantom size on the HU number accuracy and HU-density calibrations for CBCT imaging were studied. We proposed a site-specific calibration method to achieve higher accuracy in CBCT image-based dose calculation. Three configurations of the Computerized Imaging Reference Systems (CIRS) water equivalent electron density phantom were used to simulate sites including head, lungs, and lower body (abdomen/pelvis). The planning computed tomography (CT) scan was used as the baseline for comparisons. CBCT scans of these phantom configurations were performed using Varian Trilogy system in a precalibrated mode with fixed tube voltage (125 kVp), but varied mAs, SID, and cone angle. An HU-density curve was generated and evaluated for each set of scan parameters. Three HU-density tables generated using different phantom configurations with the same imaging parameter settings were s...Continue Reading

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Citations

Sep 8, 2012·Radiological Physics and Technology·Keisuke UsuiKoichi Ogawa
Sep 14, 2012·Journal of Medical Physics·Heng Siew Ping, Sivamany Kandaiya
Jun 1, 2014·Medical Physics·Xenia FaveLaurence Court
Sep 29, 2011·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Chih-Chung HuJason Chia-Hsien Cheng
Feb 18, 2016·Journal of Cancer Research and Therapeutics·Mohamathu Rafic, Paul Ravindran
Sep 15, 2015·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Lien Van De VoordePhilippe Lambin
Jul 20, 2012·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Irina FotinaDietmar Georg
Dec 23, 2011·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Ju-Young Song, Sung-Ja Ahn
Sep 5, 2015·Australasian Physical & Engineering Sciences in Medicine·Brendan WhelanLois Holloway
Feb 6, 2015·Medical Physics·Guy Amit, Thomas G Purdie
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Jun 9, 2021·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Hayate WashioTeruki Teshima

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