Dose related, comparative evaluation of a novel bone-subtraction algorithm in 64-row cervico-cranial CT angiography

European Journal of Radiology
E SiebertR Klingebiel

Abstract

Comparative evaluation of a low-dose scan protocol for a novel bone-subtraction (BS) algorithm, applicable to 64-row cervico-cranial (cc) CT angiography (MSCTA). BS algorithm assessment was performed in cadaveric phantom studies by stepwise variation of tube current and head malrotation using a 64-row CT scanner. In order to define minimum dose requirements and the rotation correction capacity, a low dose BS MSCTA protocol was defined and evaluated in 12 patients in comparison to a common manual bone removal algorithm. Standard MIPs of both modalities were evaluated in a blinded manner by two neuroradiologists for image quality composed, of vessel contour sharpness and bony vessel superposition, by using a five-point score each. Effective Dose (E) and data post-processing times were defined. In experimental studies prescan tube current could be cut down to one-sixth of post-contrast scan doses without compromise of bone-subtraction whereas incomplete subtraction appeared from four degrees head malrotation on. Prescan E amounted to additional 1.1mSv (+25%) in clinical studies. BS MSCTA performed significantly superior in terms of bony superposition for vascular segments C3-C7 (p<0.001), V1-V2, V3-V4 (p<0.05, p<0.001 respectively...Continue Reading

References

Oct 7, 2004·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·Sung Min KwonJong Beom Ra
Nov 17, 2004·Medical Physics·Marcel van StratenCornelis A Grimbergen
Nov 23, 2006·Journal of the American College of Surgeons·Garth H UtterGregory J Jurkovich

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