PMID: 9433833Feb 1, 1997Paper

Dose-response effect of risk factors for ischemic heart disease in males

Arquivos brasileiros de cardiologia
S A de Moraes, J M de Souza

Abstract

Several authors have reported hypertension, smoking and hypercholesterolemia as independent risk factors for ischemic heart disease (IHD), but few of them have investigated the existence of a linear gradient related to the levels of these exposures and IHD. We evaluated the effect of different levels of these exposures and IHD after adjusting for known confounders. The study was designed as a case-control and the period of data collection was from March/93 until February/94. The sample was composed of 547 men aged 30-69 years living in the city of São Paulo. We compared 192 cases with 355 controls (172 neighbourhood controls and 183 hospital controls). Logistic regression was the statistical method used to analyse of the data. The results showed a linear gradient for known duration of hypertension, known duration of hypercholesterolemia and daily number of cigarettes smoked. The variables known duration of diabetes mellitus and duration of smoking did not present such a tendency. Some methodological issues are presented to explain the absence of a linear gradient for known duration of diabetes mellitus and duration of smoking. It is concluded that the dose-response effect detected for known duration of hypertension, known durat...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Arquivos brasileiros de cardiologia
S A de Moraes, J M de Souza
Progress in Clinical and Biological Research
R C GoR B Copeland
Revista española de cardiología
María J Medranoinvestigadores del estudio ZACARIS
© 2021 Meta ULC. All rights reserved