PMID: 16519419Mar 8, 2006Paper

Dose response to cerebrospinal fluid drainage on cerebral perfusion in traumatic brain-injured adults

Neurosurgical Focus
M E KerrD Marion

Abstract

Intracranial hypertension remains a common complication of traumatic brain injury (TBI). Ventriculostomy drainage is a recommended therapy to decrease intracranial pressure (ICP), but little empirical evidence exists to guide treatment. The authors conducted a study to examine systematically the effect of cerebral spinal fluid (CSF) drainage on ICP and indices of cerebral perfusion. Intracranial pressure, cerebral perfusion pressure (CPP), cerebral blood flow velocity (CBFV), and near-infrared spectroscopy-determined regional cerebral oxygenation (rSO2) were measured in 58 patients (with Glasgow Coma Scale scores < or = 8) before, during, and after ventriculostomy drainage. Three randomly ordered CSF drainage protocols varied in the volume of CSF removed (1 ml, 2 ml, and 3 ml). Physiological variables were time averaged in 1-minute blocks from baseline to 10 minutes after cessation of ventricular drainage. There was a significant dose-time interaction for ICP with the three-extraction volume protocol, with incremental decreases in ICP (F [20, 1055] = 6.10; p = 0.0001). There was a significant difference in the CPP depending on the amount of CSF removed (F [2, 1787] = 3.22; p = 0.040) and across time (F [10, 9.58] = 11.9; p = 0....Continue Reading

References

Oct 1, 1977·Journal of Neurosurgery·J D MillerM J Rosner
Aug 1, 1990·The Journal of Trauma·M J Rosner, S Daughton
Jan 1, 1966·Acta neurochirurgica·T W LangfittH M Shapiro
May 1, 1984·Journal of Neurosurgery·M Kosteljanetz
Dec 1, 1995·Journal of Neurosurgery·M J RosnerA H Johnson
Feb 1, 1996·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·V MehtaR Hall
Oct 31, 1996·Annals of the New York Academy of Sciences·L C ShoweG Trinchieri
May 19, 1998·Neurological Research·A ZaunerR Bullock
Jan 9, 2001·Journal of Neurosurgical Anesthesiology·E M KerrJ Wilberger

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Citations

Dec 14, 2012·The New England Journal of Medicine·Randall M ChesnutUNKNOWN Global Neurotrauma Research Group
Jul 14, 2010·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Jennifer ExoMichael J Bell
Jun 22, 2012·Critical Care Research and Practice·P H RaboelB Romner
Jan 5, 2008·Journal of Neurosurgery·Marco D Sorani, Geoffrey T Manley
Sep 27, 2014·Critical Care Clinics·Jon Perez-BarcenaKristine H O'Phelan
Jul 3, 2013·Neurosurgery Clinics of North America·Tarek Y El AhmadiehBernard R Bendok
Feb 20, 2008·International Journal of Pediatric Otorhinolaryngology·Natalie LoundonErea Noel Garabedian
Jun 16, 2017·Journal of Neurotrauma·Omar S AkbikHoward Yonas
Apr 5, 2008·Current Opinion in Critical Care·Thomas LescotLouis Puybasset
Oct 7, 2005·The Journal of Nervous and Mental Disease·Eric B ElbogenRichard Van Dorn
Jul 8, 2020·Journal of Clinical Medicine·Charlene Y C ChauAngelos G Kolias
Sep 13, 2019·Journal of Clinical Medicine·Charlene Y C ChauAngelos G Kolias
Nov 5, 2005·AACN Clinical Issues·Karen March
Dec 14, 2018·Neurocritical Care·Xiuyun LiuXiao Hu
Apr 1, 2020·Neurocritical Care·Aaron M CookLori Shutter
Mar 5, 2020·Neurology India·Hitesh Kumar GurjarKanwaljeet Garg
Mar 1, 2020·Current Treatment Options in Neurology·Benjamin E ZusmanRuchira M Jha

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