PMID: 8598371Mar 1, 1996Paper

Dose volume assessment of high dose rate 192Ir endobronchial implants

International Journal of Radiation Oncology, Biology, Physics
C B SawA Wu

Abstract

To study the dose distributions of high dose rate (HDR) endobronchial implants using the dose nonuniformity ratio (DNR) and three volumetric irradiation indices. Multiple implants were configured by allowing a single HDR 192Ir source to step through a length of 6 cm along an endobronchial catheter. Dwell times were computed to deliver a dose of 5 Gy to points 1 cm away from the catheter axis. Five sets of source configurations, each with different dwell position spacings from 0.5 to 3.0 cm, were evaluated. Three-dimensional (3D) dose distributions were then generated for each source configuration. Differential and cumulative dose-volume curves were generated to quantify the degree of target volume coverage, dose nonuniformity within the target volume, and irradiation of tissues outside the target volume. Evaluation of the implants were made using the DNR and three volumetric irradiation indices. The observed isodose distributions were not able to satisfy all the dose constraints. The ability to optimally satisfy the dose constraints depended on the choice of dwell position spacing and the specification of the dose constraint points. The DNR and irradiation indices suggest that small dwell position spacing does not result in a m...Continue Reading

References

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Jun 15, 1993·International Journal of Radiation Oncology, Biology, Physics·C B SawA Wu

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Citations

Dec 10, 1997·International Journal of Radiation Oncology, Biology, Physics·T W LeungS K O
Mar 5, 1998·International Journal of Radiation Oncology, Biology, Physics·C B SawD Ulewicz
Jul 27, 1999·International Journal of Radiation Oncology, Biology, Physics·V Y WongC M Wong
Dec 24, 1998·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·W SchumerM Geso

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