Dosimetric comparison between IMRT and VMAT in irradiation for peripheral and central lung cancer

Oncology Letters
Yi LiJuan Ren

Abstract

The aim of the present study was to compare intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) in irradiation of lung cancer. Plans of 14 patients were compared. The results demonstrated that in peripheral lung cancer, V5 (%) of the lung in partial-arc (PA)-VMAT was decreased compared with IMRT, single-arc (SA)-, and double partial-arc (2PA)-VMAT. V30 (%) of the lung in IMRT was decreased compared with SA-, PA- and 2PA-VMAT. In the case of planning target volume (PTV) not encompassing the mediastinum in central lung cancer, the conformality index (CI) and heterogeneity index (HI) of SA-VMAT was improved compared with IMRT, PA-, and 2PA-VMAT. The received dose of heart in SA-VMAT was higher compared with IMRT, PA- and 2PA-VMAT. V30 (%) and V5 (%) of the lung in IMRT was higher compared with SA-, PA- and 2PA-VMAT; V10 (%) of the lung in 2PA was decreased compared with IMRT, SA- and PA. In the case of PTV encompassing the mediastinum in central lung cancer, the HI and CI of 2PA was improved compared with IMRT, SA- and PA-VMAT. The received dose of heart in 2PA was higher compared with IMRT, SA- and PA-VMAT. V30 (%) and V5 (%) of the lung in 2PA-VMAT was higher compared with IMRT, SA- and PA-VM...Continue Reading

References

Oct 1, 1982·Physics in Medicine and Biology·A BrahmeI Lax
Feb 1, 1997·International Journal of Radiation Oncology, Biology, Physics·A van't RietW van der Zee
Sep 16, 1999·International Journal of Radiation Oncology, Biology, Physics·M V GrahamC A Perez
Dec 1, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·A PollackI Rosen
Oct 13, 2001·International Journal of Radiation Oncology, Biology, Physics·M L HernandoP A Lind
Jul 17, 2003·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Tiziana RancatiGiovanni Mauro Cattaneo
Apr 28, 2004·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Line ClaudeChristian Carrie
Mar 9, 2005·International Journal of Radiation Oncology, Biology, Physics·Stephanie T H PeetersPeter C M Koper
Feb 16, 2006·Medical Physics·Klaus Bratengeier
Jan 24, 2007·International Journal of Radiation Oncology, Biology, Physics·John M SchallenkampYolanda I Garces
Nov 13, 2007·International Journal of Radiation Oncology, Biology, Physics·Patrick A KupelianArul Mahadevan
Aug 12, 2008·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Luca CozziAntonella Fogliata
Feb 3, 2009·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Alessandro ClivioLuca Cozzi
Apr 14, 2009·International Journal of Radiation Oncology, Biology, Physics·Wilko F A R VerbakelSuresh Senan
May 12, 2009·International Journal of Radiation Oncology, Biology, Physics·Frank J LagerwaardSuresh Senan
Jun 23, 2009·International Journal of Radiation Oncology, Biology, Physics·Pengpeng ZhangGig Mageras
Jun 26, 2009·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Wilko F A R VerbakelFrank J Lagerwaard
Jul 7, 2009·International Journal of Radiation Oncology, Biology, Physics·Frank J LagerwaardSuresh Senan
Sep 8, 2009·International Journal of Radiation Oncology, Biology, Physics·Q Jackie WuFang-Fang Yin
Sep 15, 2009·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Matthias GuckenbergerMichael Flentje
Sep 22, 2009·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Dirk WolffFrank Lohr
Nov 26, 2009·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Albert S ZacariasMichael D Mills
Jan 2, 2010·International Journal of Radiation Oncology, Biology, Physics·Sua YooFang-Fang Yin
Jan 27, 2010·International Journal of Radiation Oncology, Biology, Physics·Martha M MatuszakAlvaro Martinez
Feb 2, 2010·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Samuel D McGrathInga S Grills
Mar 2, 2010·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Anders BertelsenCarsten Brink
Nov 16, 2010·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Chin Loon OngSuresh Senan
Feb 9, 2011·International Journal of Radiation Oncology, Biology, Physics·Andrea HoltEugène M F Damen
Aug 21, 2012·International Journal of Radiation Oncology, Biology, Physics·Enzhuo M QuanXiaodong Zhang

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Citations

Mar 27, 2021·World Journal of Clinical Oncology·Felipe CouñagoFrancesc Casas

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Methods Mentioned

BETA
RIP

Software Mentioned

SmartArc
SAS
SA
2PA
Pinnacle3
VMAT
PA

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