Dosimetric comparison using different multileaf collimeters in intensity-modulated radiotherapy for upper thoracic esophageal cancer.

Radiation Oncology
Youling GongQingfeng Jiang

Abstract

To study the impacts of multileaf collimators (MLC) width [standard MLC width of 10 mm (sMLC) and micro-MLC width of 4 mm (mMLC)] in the intensity-modulated radiotherapy (IMRT) planning for the upper thoracic esophageal cancer (UTEC). 10 patients with UTEC were retrospectively planned with the sMLC and the mMLC. The monitor unites (MUs) and dose volume histogram-based parameters [conformity index (CI) and homogeneous index (HI)] were compared between the IMRT plans with sMLC and with mMLC. The IMRT plans with the mMLC were more efficient (average MUs: 703.1 +/- 68.3) than plans with the sMLC (average MUs: 833.4 +/- 73.8) (p < 0.05). Also, compared to plans with the sMLC, the plans with the mMLC showed advantages in dose coverage of the planning gross tumor volume (Pgtv) (CI 0.706 +/- 0.056/HI 1.093 +/- 0.021) and the planning target volume (PTV) (CI 0.707 +/- 0.029/HI 1.315 +/- 0.013) (p < 0.05). In addition, the significant dose sparing in the D5 (3260.3 +/- 374.0 vs 3404.5 +/- 374.4)/gEUD (1815.1 +/- 281.7 vs 1849.2 +/- 297.6) of the spinal cord, the V10 (33.2 +/- 6.5 vs 34.0 +/- 6.7), V20 (16.0 +/- 4.6 vs 16.6 +/- 4.7), MLD (866.2 +/- 174.1 vs 887.9 +/- 172.1) and gEUD (938.6 +/- 175.2 vs 956.8 +/- 171.0) of the lungs were o...Continue Reading

References

Feb 9, 1999·Medical Physics·P XiaA Boyer
Jul 1, 1999·International Journal of Radiation Oncology, Biology, Physics·H D KuboC T Pappas
Jul 7, 1999·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·V P CosgroveR E Wurm
Nov 25, 2003·International Journal of Radiation Oncology, Biology, Physics·Jacqueline Elizabeth MonkPiers Nicholas Plowman
Mar 31, 2004·International Journal of Radiation Oncology, Biology, Physics·James M GalvinUNKNOWN American Association of Physicists in Medicine
Mar 24, 2005·American Journal of Physical Medicine & Rehabilitation·Anthony B Ward
Apr 9, 2005·International Journal of Radiation Oncology, Biology, Physics·Pavel DvorakRichard Pötter
May 10, 2005·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Simeon NillUwe Oelfke
Jun 1, 2005·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Lu WangCharlie C M Ma
Nov 25, 2005·Physics in Medicine and Biology·I PatelM C Kirby
May 23, 2006·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Bram van AsselenEugene M F Damen
Aug 21, 2007·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Klaus BratengeierMichael Flentje
Jan 18, 2008·Physics in Medicine and Biology·E Ludlum, P Xia
May 29, 2012·Asian Pacific Journal of Cancer Prevention : APJCP·Saginbek IgissinovSaken Kozhakhmetov

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Citations

Jan 18, 2014·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Alessandra CarosiRiccardo Santoni
Oct 9, 2013·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Shichao WangNianyong Chen
May 20, 2021·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Hui YanYi-Min Hu

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