Dosimetric impact of online correction via cone-beam CT-based image guidance for stereotactic lung radiotherapy

International Journal of Radiation Oncology, Biology, Physics
Ana Paula GaleraniDi Yan

Abstract

To evaluate the dosimetric impact of online cone-beam computed tomography (CBCT) guided correction in lung stereotactic body radiation therapy (SBRT). Twenty planning and 162 CBCT images from 20 patients undergoing lung SBRT were analyzed. The precorrection CBCT (CBCT after patient setup, no couch correction) was registered to planning CT using soft tissue; couch shift was applied, with a second CBCT for verification (postcorrection CBCT). Targets and normal structures were delineated on CBCTs: gross tumor volume (GTV), clinical target volume (CTV), cord, esophagus, lung, proximal bronchial tree, and aorta. Dose distributions on all organs manifested on each CBCT were compared with those planned on the CT. Without CBCT guided target position correction, target dose reduced with respect to treatment plan. Mean and standard deviation of treatment dose discrepancy from the plan were -3.2% (4.9%), -2.1% (4.4%), -6.1% (10.7%), and -3.5% (7%) for GTV D(99%), GTV D(95%), CTV D(99%), and CTV D(95%), respectively. With CBCT correction, the results were -0.4% (2.6%), 0.1% (1.7%), -0.3% (4.2%), and 0.5% (3%). Mean and standard deviation of the difference in normal organ maximum dose were 2.2% (6.5%) before correction and 2.4% (5.9%) after...Continue Reading

References

Jan 9, 1998·International Journal of Radiation Oncology, Biology, Physics·G S SibleyL R Prosnitz
Oct 19, 1999·International Journal of Radiation Oncology, Biology, Physics·D A JaffrayJ W Wong
Apr 24, 2001·International Journal of Radiation Oncology, Biology, Physics·K M Langen, D T Jones
Jun 19, 2001·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·M EngelsmanB J Mijnheer
Nov 3, 2004·International Journal of Radiation Oncology, Biology, Physics·Louis PottersUNKNOWN American College of Radiology
May 14, 2005·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Daniel LétourneauAlvaro A Martinez
Aug 24, 2005·International Journal of Radiation Oncology, Biology, Physics·Ronald C McGarryRobert D Timmerman
Sep 20, 2005·International Journal of Radiation Oncology, Biology, Physics·Yasushi NagataMasahiro Hiraoka
Jun 27, 2006·International Journal of Radiation Oncology, Biology, Physics·Marco SchwarzEugène M F Damen
Sep 5, 2006·International Journal of Radiation Oncology, Biology, Physics·Lu WangCharlie C-M Ma
Jun 16, 2007·International Journal of Radiation Oncology, Biology, Physics·Inga S GrillsLarry L Kestin
Nov 22, 2007·International Journal of Radiation Oncology, Biology, Physics·Inga S GrillsDi Yan
Jan 1, 2008·International Journal of Radiation Oncology, Biology, Physics·Frank J LagerwaardS Senan

❮ Previous
Next ❯

Citations

Sep 6, 2012·Australasian Physical & Engineering Sciences in Medicine·Shamurailatpam Dayananda SharmaMalhotra Heigrujam
Aug 31, 2012·Radiology and Oncology·Poonam YadavBhudatt R Paliwal
May 3, 2011·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Judit Boda-HeggemannMatthias Guckenberger
Feb 7, 2012·Acta Oncologica·Einar WaldelandEirik Malinen
Nov 11, 2015·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Sandie Carolyn WattLois C Holloway
Dec 20, 2011·Seminars in Radiation Oncology·Alexis BujoldLaura A Dawson
May 29, 2012·International Journal of Radiation Oncology, Biology, Physics·Dominique C van RooijenArjan Bel
Dec 3, 2014·International Journal of Radiation Oncology, Biology, Physics·Victor S MangonaInga Siiner Grills
Mar 19, 2014·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Larry KestinUNKNOWN Elekta Lung Research Group
Jun 25, 2021·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Celia Juan-CruzJan-Jakob Sonke
Jul 18, 2021·Journal of Applied Clinical Medical Physics·Geoffrey BaranJay W Burmeister

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.