Dosimetrically determined doses of radioiodine for the treatment of metastatic thyroid carcinoma

Thyroid : Official Journal of the American Thyroid Association
Douglas Van NostrandLeonard Wartofsky

Abstract

In the absence of definitive studies relating radioiodine dose to outcomes, selection of a dose of radioiodine to treat metastatic thyroid carcinoma is problematic, and several approaches have been used. These include empiric fixed doses and doses used on dosimetric approaches specific for each patient. This paper is a review of the rationale and technique for dosimetrically-determined doses of radioiodine for the treatment of metastatic thyroid carcinoma. This review (1) discusses the alternatives for selection of a dose, (2) discusses the two major approaches for determining radioiodine doses dosimetrically, (3) briefly reviews several modifications of these approaches, (4) reviews the literature regarding the results, (5) discusses the side effects of these different approaches, and (6) concludes with recommendations for patient management and future research. This review does not address use of dosimetrically-determined doses of radioiodine for the initial ablation of thyroid tissue postoperatively.

References

Jan 1, 1978·Seminars in Nuclear Medicine·W H Beierwaltes
Mar 1, 1979·Clinics in Endocrinology and Metabolism·C J Edmonds
May 1, 1977·The British Journal of Radiology·A C McEwan
Jul 1, 1976·Medical Physics·S R ThomasJ G Kereiakes
Jan 1, 1989·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·T SchlesingerV R McCready
Apr 1, 1985·Seminars in Nuclear Medicine·J E FreitasB Shapiro
Oct 1, 1986·The Journal of Clinical Endocrinology and Metabolism·M SchlumbergerC Parmentier
Sep 1, 1985·The Medical Clinics of North America·R D Leeper
Oct 1, 1971·Seminars in Nuclear Medicine·E E Pochin
Feb 1, 1972·The British Journal of Radiology·E J Hall
Nov 23, 1970·JAMA : the Journal of the American Medical Association·V M VarmaJ E Copp
Oct 20, 1983·The New England Journal of Medicine·H R MaxonE L Saenger
Jul 1, 1980·Clinics in Endocrinology and Metabolism·R D Leeper, K Shimaoka
Apr 1, 1997·Thyroid : Official Journal of the American Thyroid Association·M SchlumbergerF Pacini
Apr 1, 1997·Seminars in Nuclear Medicine·J C Reynolds, J Robbins
Dec 7, 1946·Journal of the American Medical Association·S M SEIDLINE OSHRY

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Citations

May 21, 2008·European Journal of Nuclear Medicine and Molecular Imaging·Michael LassmannUNKNOWN EANM Dosimetry Committee
Dec 25, 2009·European Journal of Nuclear Medicine and Molecular Imaging·Frederik A VerburgMarkus Luster
Mar 24, 2010·European Journal of Nuclear Medicine and Molecular Imaging·Massimo SalvatoriMassimo Eugenio Dottorini
Jan 31, 2007·Thyroid : Official Journal of the American Thyroid Association·David C Howlett
Jan 20, 2006·Thyroid : Official Journal of the American Thyroid Association·David S CooperUNKNOWN American Thyroid Association Guidelines Taskforce
Oct 29, 2009·Thyroid : Official Journal of the American Thyroid Association·UNKNOWN American Thyroid Association (ATA) Guidelines Taskforce on Thyroid Nodules and Differentiated Thyroid CancerR Michael Tuttle
Oct 5, 2010·Thyroid : Official Journal of the American Thyroid Association·Douglas Van NostrandGurudev Gadwale
Dec 17, 2009·Thyroid : Official Journal of the American Thyroid Association·Douglas Van Nostrand
Feb 9, 2012·Thyroid : Official Journal of the American Thyroid Association·Joanna Klubo-GwiezdzinskaLeonard Wartofsky
Oct 24, 2007·Radiation Protection Dosimetry·Alfredo SernaManuel Canteras
Feb 9, 2012·Journal of Pediatric Endocrinology & Metabolism : JPEM·Leilei Yuan, Jigang Yang
Jan 10, 2013·Medical Physics·Pablo MinguezJose Cruz Fombellida
Apr 23, 2014·Nuclear Medicine Communications·Armaghan Fard-EsfahaniMohammad Eftekhari
Jun 27, 2012·Endocrine·Leonard Wartofsky, Douglas Van Nostrand
Apr 13, 2011·European Journal of Nuclear Medicine and Molecular Imaging·George SgourosRichard L Wahl
Nov 2, 2014·Seminars in Nuclear Medicine·Adina L Alazraki, Kiery A Braithwaite
Sep 23, 2008·Expert Opinion on Pharmacotherapy·Jennifer A Sipos, Ernest L Mazzaferri
Nov 29, 2011·Seminars in Nuclear Medicine·Charles M IntenzoSung M Kim
Jun 28, 2011·Methods : a Companion to Methods in Enzymology·Frederik A VerburgFelix M Mottaghy
May 17, 2011·Radiologic Clinics of North America·Judith M Joyce, Andrew Swihart
Jun 1, 2010·Otolaryngologic Clinics of North America·Amin Sabet, Matthew Kim
Oct 20, 2009·The Surgical Clinics of North America·James Suliburk, Leigh Delbridge
Sep 12, 2015·Thyroid : Official Journal of the American Thyroid Association·Frank AtkinsLeonard Wartofsky
Dec 2, 2008·Best Practice & Research. Clinical Endocrinology & Metabolism·Christoph ReinersMarkus Luster
Jan 8, 2008·Surgical Oncology Clinics of North America·Timothy A ManzonePrakash Seshadri
Aug 4, 2007·Endocrinology and Metabolism Clinics of North America·Douglas Van Nostrand, Leonard Wartofsky
Jul 6, 2014·Clinical Endocrinology·Petros PerrosUNKNOWN British Thyroid Association
Nov 28, 2015·Surgical Oncology Clinics of North America·Jenny Y Yoo, Michael T Stang
Jun 22, 2010·Clinical Oncology : a Journal of the Royal College of Radiologists·M Chao
May 10, 2016·Molecular Therapy : the Journal of the American Society of Gene Therapy·Sarah UrnauerChristine Spitzweg
Dec 16, 2017·SAGE Open Medical Case Reports·Brandon A HowardRobert E Reiman
Aug 15, 2018·Thyroid : Official Journal of the American Thyroid Association·Douglas Van Nostrand
Oct 30, 2018·Clinical Nuclear Medicine·Anca M AvramDavid T Hughes
Feb 24, 2016·The Journal of Clinical Endocrinology and Metabolism·Athanasios BikasDouglas Van Nostrand
Apr 25, 2019·Thyroid : Official Journal of the American Thyroid Association·Di WuDouglas Van Nostrand
Aug 10, 2011·Nature Reviews. Endocrinology·Christoph ReinersFrederik A Verburg
Oct 5, 2017·Clinical Medicine : Journal of the Royal College of Physicians of London·Nitasha Singh, Val Lewington

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