PMID: 6110584Jan 1, 1980Paper

Double-blind comparison of intravenously injected butorphanol and meperidine in parturients

International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics
E J QuilliganM J Donahue

Abstract

One hundred women with moderate-to-very-severe prepartum pain participated in a double-blind study of intravenously injected butorphanol and meperidine that compared the analgesic properties, effect on the process of labor, condition of the newborn and the incidence of side effects associated with the two drugs. Cervical dilation, infant birth weight and Apgar scores were not significantly different between the test groups. The mean fetal heart rate for the butorphanol group was significantly faster than that of the meperidine group. Butorphanol provided significantly more analgesia than meperidine at 30 minutes and one hour after administration, based on pain intensity and pain relief scores. Some side effects, including sedation, dizziness, lightheadedness, nausea, vomiting and pain at the injection site, were reported for both drugs.

References

Jan 1, 1977·Canadian Anaesthetists' Society Journal·F M GallowayF S Caruso
Sep 1, 1978·Canadian Anaesthetists' Society Journal·A L Maduska, M Hajghassemali
Jan 1, 1979·The Journal of International Medical Research·R HodgkinsonF J Husain
Jun 1, 1976·Clinical Pharmacology and Therapeutics·H NagashimaF F Foldes
Sep 1, 1976·Clinical Pharmacology and Therapeutics·M S GilbertF S Caruso
Nov 1, 1975·Clinical Pharmacology and Therapeutics·A B DobkinF S Caruso

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Citations

May 4, 2011·Journal of Midwifery & Women's Health·Deborah Anderson
Sep 9, 2010·The Cochrane Database of Systematic Reviews·Roz UllmanTherese Dowswell
Jun 1, 1995·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·W M SplinterL Komocar
Jul 13, 2012·The Cochrane Database of Systematic Reviews·Mohammad OthmanJames P Neilson
Jul 30, 2011·The Journal of Small Animal Practice·E Vettorato, S Bacco
Jun 6, 2018·The Cochrane Database of Systematic Reviews·Lesley A SmithAnna Cuthbert
Jan 1, 1982·Neuroscience and Biobehavioral Reviews·I S ZagonE Zagon

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