PMID: 9551778Apr 29, 1998Paper

Double-blind placebo controlled trial of dextrose tablets and nicotine patch in smoking cessation

Psychopharmacology
Robert West, N Willis

Abstract

In a placebo-controlled double-blind trial 308 smokers were individually randomly allocated to one of four groups: 1) 3 g dextrose tablets and 15 mg nicotine transdermal patch; 2) dextrose and placebo patch; 3) placebo tablets and nicotine patch; 4) placebo tablets and placebo patch. Patients were scheduled to attend weekly smokers clinic sessions starting 1 week before the quit date and continue for 4 weeks after that date. The primary outcome variable was biochemically verified abstinence at the final session, four weeks after the scheduled quit date. The proportion of smokers abstinent in the four groups was as follows: 49% - dextrose plus active patch; 44% - dextrose plus placebo patch; 36% - placebo tablet plus active patch; 30% - placebo tablet plus placebo patch. The difference between the dextrose and placebo tablets (13%) was statistically significant (P < 0.01, one-tailed); the difference between the active and placebo patches (6%) was not. There was no significant difference between the effect of the dextrose when accompanied by active versus placebo patches. There was no significant effect of dextrose on weight. The results suggest that dextrose supplementation to the diet may be a cheap and simple aid to giving up ...Continue Reading

Citations

Aug 4, 2004·Psychopharmacology·Ivan BerlinOdile Spreux-Varoquaux
Oct 28, 2009·Psychopharmacology·Robert WestEleni Vangeli
Mar 3, 2010·Psychopharmacology·Jonathan FouldsMichelle T Bover-Manderski
Nov 26, 2010·Journal of Health Communication·Michael UssherGillian Rowlands
Oct 3, 2008·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Scott Rick, George Loewenstein
Sep 25, 2008·BMC Public Health·Michael UssherIsaac Manyonda
Sep 11, 2012·Addictive Behaviors·Michael UssherTim Coleman
Aug 17, 2016·Behavioral Sciences·Audrey E ParrishMichael J Beran
May 6, 2008·Personality and Social Psychology Review : an Official Journal of the Society for Personality and Social Psychology, Inc·Matthew T Gailliot, Roy F Baumeister
Jan 7, 2009·Therapeutic Advances in Respiratory Disease·Laura CarrozziGiovanni Viegi
Jan 20, 2012·The Cochrane Database of Systematic Reviews·Amanda C FarleyPaul Aveyard
Jun 1, 2018·The Cochrane Database of Systematic Reviews·Jamie Hartmann-BoyceTim Lancaster

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