PMID: 38705Jan 1, 1979

Double blind randomized trial of metopimazine: for postoperative nausea and vomiting after cholecystectomy

Annales de l'anesthésiologie française
C RodaryJ N Maillard

Abstract

Eighty-four patients submitted to cholecystectomy were randomly assigned in a double-blind study either to an intravenous dose of 10 mg of metopimazine, three times D-1, for two days or to an identically administered placebo. A definite superiority of metopimazine as an anti-emetic drug was demonstrated. General acceptance was excellent, but arterial pressure might be looked over closely when metopimazine was administered intravenously immediately after a general anesthesia.

Related Concepts

Cholecystectomy Procedure
Clinical Trials
Double-Blind Method
Isonipecotic Acids
Phenothiazines
Postoperative Complications
Vomiting

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