PMID: 6134429Mar 1, 1983

Double-blind trial of triazolam 0.5 mg vs. nitrazepam 5 mg in outpatients

Acta Psychiatrica Scandinavica
P A Ellingsen

Abstract

In a double-blind, cross-over trial, triazolam (0.5 mg) was compared with nitrazepam (5 mg) in patients with disturbed sleep. Each drug was given once, with a 48-h interval, to 40 outpatients. Quality, duration, and latency of sleep, and number of awakenings during the night, showed a significant difference in favour of triazolam. An overall evaluation of sleep also showed triazolam to be superior to nitrazepam. Both drugs seemed to reduce dream activity and to alter the character of the dreams. There was no significant difference in side effects.

References

Jan 1, 1975·Psychopharmacologia·G VogelK Sexton
Sep 1, 1974·Pharmakopsychiatrie, Neuro-Psychopharmakologie·T M ItilJ Marasa
Jan 1, 1981·Clinical Pharmacology and Therapeutics·F S EbertsR W Vliek
Sep 1, 1981·Acta Psychiatrica Scandinavica·O Lingjaerde, T Bratlid
Jan 1, 1981·British Journal of Clinical Pharmacology·D J GreenblattR I Shader

Citations

Jan 1, 1990·Journal of Psychoactive Drugs·V L Martin
Dec 22, 2016·Journal of Clinical Medicine·Mark B DetweilerBrian W Lutgens
Mar 13, 2008·Australasian Psychiatry : Bulletin of Royal Australian and New Zealand College of Psychiatrists·Alex HolmesAndy Innis
Nov 24, 2020·Frontiers in Neurology·Alain Nicolas, Perrine M Ruby

Related Concepts

Vigilance, Cortical
Double-Blind Method
Transient Insomnia
Imeson
Reaction Time
Anti-Anxiety Effect
Trilam

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