Double Centrifugation Versus Single Centrifugation of Bone Marrow Aspirate Concentrate in Sinus Floor Elevation: A Pilot Study

The International Journal of Oral & Maxillofacial Implants
Thiago Altro de OliveiraAndré Antonio Pelegrine

Abstract

To evaluate the regenerative results of the addition of bone marrow aspirate concentrate, using a single or double centrifugation protocol, to a xenogeneic bone graft in sinus floor elevation. Using a randomized, controlled pilot study design in 15 consecutive patients, sinus floor elevation procedures were performed with a xenogenous bone graft alone (control group, CG) or associated with bone marrow aspirate concentrate obtained by single centrifugation (single centrifugation group, SCG) or double centrifugation (double centrifugation group, DCG). In the patients in the single and double centrifugation groups, bone marrow was harvested from the iliac bone. Six months after the grafting procedures, bone biopsy specimens were obtained during implant placement and were analyzed by histomorphometry. Histomorphometric analysis revealed a great amount of vital mineralized tissue in SCG followed by DCG when compared with the CG (38.44 ± 12.34%, 34.63 ± 9.84%, and 27.30 ± 5.55%, respectively). SCG and DCG presented smaller amounts of nonvital mineralized tissue when compared with the CG (13.70 ± 7.50%, 19.63 ± 8.35%, and 22.79 ± 9.60%, respectively), thus presenting higher levels of resorption. Although these differences were not sta...Continue Reading

Citations

Jan 10, 2019·Journal of Clinical Periodontology·Siddharth ShanbhagKamal Mustafa
Oct 13, 2017·Frontiers in Cell and Developmental Biology·Ruggero Rodriguez Y BaenaSaturnino M Lupi
Apr 12, 2018·Brazilian Oral Research·André Antonio PelegrinePeter Keyren Moy
Jun 15, 2021·The British Journal of Oral & Maxillofacial Surgery·J V D S CanellasP J D Medeiros

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