Double pass 595 nm pulsed dye laser at a 6 minute interval for the treatment of port-wine stains is not more effective than single pass

Lasers in Surgery and Medicine
M A D PetersJohan F Beek

Abstract

Pulsed dye laser (PDL) is the first choice for treatment of port wine stains (PWS). However, outcome is highly variable and only a few patients achieve complete clearance. The objective of the study was to compare efficacy and safety of single pass PDL with double pass PDL at a 6 minute interval. We conducted a randomized within-patient controlled study on PWS resistant to multiple single pass PDL treatments. In each patient two similar PWS areas were randomly allocated to PDL treatment (595 nm, 7 mm spot size, 1.5 mseconds pulse duration) using, as a control treatment, a single pass (12 J/cm(2)) or, as a new treatment, a double pass PDL (11 J/cm(2), second pass 6 minutes after the first pass). Both test areas were treated two times, 8 weeks apart. PWS clearance was assessed by two blinded dermatologists, and by color measurement (L*a*b) using reflectance spectroscopy, at 3 months follow-up. Sixteen out of 17 included patients completed follow-up. The mean number of treatments before inclusion was 15. Overall color assessed by spectrophotometer showed no improvement for either single or double pass PDL. Blinded Physician Global Assessment and Patient Global Assessment showed a high variability in outcome, with mostly only moder...Continue Reading

References

Jun 1, 1989·The Journal of Investigative Dermatology·O T TanA K Kurban
Jun 1, 1988·Annals of Plastic Surgery·M Malm, M Carlberg
Mar 1, 1985·American Journal of Diseases of Children·A HellerI B Pless
Apr 16, 1998·The New England Journal of Medicine·C M van der HorstM J van Gemert
Oct 10, 1998·The British Journal of Dermatology·S W Lanigan
Feb 26, 1999·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·K V LeI J Frieden
Dec 14, 1999·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·P L Bencini
Dec 29, 2000·Physics in Medicine and Biology·W VerkruysseJ S Nelson
Mar 7, 2001·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·S LorenzU Hohenleutner
Apr 12, 2001·The British Journal of Dermatology·M M ChowdhuryS W Lanigan
Feb 6, 2004·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Thomas E RohrerVivek Iyengar
Sep 21, 2004·The British Journal of Dermatology·S W Lanigan, S M Taibjee
Aug 27, 2005·The British Journal of Dermatology·A Yung, R Sheehan-Dare
Sep 21, 2005·Archives of Facial Plastic Surgery·Kristen M KellyJ Stuart Nelson
Jan 31, 2006·Lasers in Surgery and Medicine·Emil TanghettiMirko Mirkov
Mar 25, 2006·Annals of Plastic Surgery·Taro KonoHiroyuki Sakurai
Apr 26, 2006·The British Journal of Dermatology·D J McGill, I R Mackay
Jul 31, 2007·Journal of the American Academy of Dermatology·Zaid F Jasim, Julian M Handley
Apr 29, 2009·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Tina S Alster, Elizabeth L Tanzi
Jul 10, 2009·Lasers in Surgery and Medicine·Leonid IziksonR Rox Anderson
Apr 9, 2011·Lasers in Medical Science·Ratna RajaratnamDenis Dudley
Aug 1, 1978·Psychiatry·S Michael Kalick

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Citations

Oct 25, 2012·Lasers in Medical Science·Katlein FrançaKeyvan Nouri
Oct 26, 2012·Journal of the European Academy of Dermatology and Venereology : JEADV·A M van DroogeA Wolkerstorfer
May 2, 2015·Journal of the European Academy of Dermatology and Venereology : JEADV·M AdamičP Boixeda
May 10, 2016·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Sujay Khandpur, Vinod K Sharma
Feb 1, 2018·Journal of Cosmetic and Laser Therapy : Official Publication of the European Society for Laser Dermatology·M Ingmar van RaathMichal Heger
Apr 3, 2021·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Pedram NoormohammadpourZahra Razavi
Jun 8, 2021·Photobiomodulation, Photomedicine, and Laser Surgery·Jiafang ZhuXiaoxi Lin

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