Double reading of automated breast ultrasound with digital mammography or digital breast tomosynthesis for breast cancer screening

Clinical Imaging
Janie M LeeConstance D Lehman

Abstract

To evaluate the impact of double reading automated breast ultrasound (ABUS) when added to full field digital mammography (FFDM) or digital breast tomosynthesis (DBT) for breast cancer screening. From April 2014 to June 2015, 124 women with dense breasts and intermediate to high breast cancer risk were recruited for screening with FFDM, DBT, and ABUS. Readers used FFDM and DBT in clinical practice and received ABUS training prior to study initiation. FFDM or DBT were first interpreted alone by two independent readers and then with ABUS. All recalled women underwent diagnostic workup with at least one year of follow-up. Recall rates were compared using the sign test; differences in outcomes were evaluated using Fisher's exact test. Of 121 women with complete follow-up, all had family (35.5%) or personal (20.7%) history of breast cancer, or both (43.8%). Twenty-four women (19.8%) were recalled by at least one modality. Recalls increased from 5.0% to 13.2% (p = 0.002) when ABUS was added to FFDM and from 3.3% to 10.7% (p = 0.004) when ABUS was added to DBT. Findings recalled by both readers were more likely to result in a recommendation for short term follow-up imaging or tissue biopsy compared to findings recalled by only one read...Continue Reading

Citations

Mar 18, 2020·AJR. American Journal of Roentgenology·Reni S Butler, Regina J Hooley
May 16, 2020·Computational and Mathematical Methods in Medicine·Xiaobo LaiRuipeng Li
Aug 28, 2021·Journal of Personalized Medicine·Ioana Boca BeneSorin Marian Dudea

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