PMID: 12780905Jun 5, 2003Paper

Double stapled ileal pouch anal anastomosis (DS-IPAA) for mucosal ulcerative colitis (MUC): is there a correlation between the tissue type in the circular stapler donuts and in follow-up biopsy?

Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland
N SaigusaB Belin

Abstract

This study aims to assess the correlation between the tissue types found in the circular stapler donut at the time of initial double-stapled ileal pouch-anal anastomosis (DS-IPAA) and during subsequent periodic routine random biopsy. Secondarily, we sought to assess the risk of dysplasia, carcinoma or mucosal ulcerative colitis (MUC) recurrence in the retained mucosa. The pathology reports of 91 patients (48 males, 43 females) who were operated upon for MUC from September 1988 to June 1997 and were reviewed and had two follow up visits for biopsy. The histological features of the distal donuts and biopsies of retained mucosa obtained at yearly interval follow-up were assessed in order to determine the epithelial tissue type (columnar, transitional and squamous), inflammation, recurrence of MUC and presence of dysplasia or malignancy. Median age at surgery was 43 (range 15-71) years and duration of MUC was 9.6 (range 0.3-42) years prior to surgery. The anastomosis was performed at a median height of 1.0 (range 0-2.5) cm cephalad to the dentate line and biopsy follow-up was undertaken at median 34 (range 2-110) months after DS-IPAA. The distal donuts were analysed in all cases, as were 305 follow-up biopsies (median 3.4; range 1-...Continue Reading

References

Nov 1, 1992·Diseases of the Colon and Rectum·S L SchmittD G Jagelman
Mar 1, 1992·Diseases of the Colon and Rectum·D PuthuP Venugopal
Sep 1, 1989·The British Journal of Surgery·D W KingT A Cook
Jan 1, 1987·Diseases of the Colon and Rectum·P R O'ConnellR L Telander
Apr 1, 1985·Pathology·B C Morson
Jul 1, 1995·Diseases of the Colon and Rectum·J C Rodriguez-SanjuanJ Castillo
Sep 1, 1995·Archives of Surgery·K W GilchristJ R Starling
Aug 1, 1996·Diseases of the Colon and Rectum·V E PricoloF I Luks
Nov 21, 1998·The British Journal of Surgery·M W Thompson-FawcettN J Mortensen

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