Double-wire sternal closure technique in bovine animal models for total artificial heart implant

The International Journal of Artificial Organs
Jamshid H KarimovK Fukamachi

Abstract

In vivo preclinical testing of mechanical circulatory devices requires large animal models that provide reliable physiological and hemodynamic conditions by which to test the device and investigate design and development strategies. Large bovine species are commonly used for mechanical circulatory support device research. The animals used for chronic in vivo support require high-quality care and excellent surgical techniques as well as advanced methods of postoperative care. These techniques are constantly being updated and new methods are emerging.We report results of our double steel-wire closure technique in large bovine models used for Cleveland Clinic's continuous-flow total artificial heart development program. This is the first report of double-wire sternal fixation used in large bovine models.

References

Sep 29, 2009·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Kiyotaka FukamachiLeonard A R Golding
Jul 4, 2012·Artificial Organs·Mariko KobayashiLeonard A R Golding
Jul 16, 2015·The Journal of Thoracic and Cardiovascular Surgery·Jamshid H KarimovKiyotaka Fukamachi

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Citations

Dec 20, 2015·Artificial Organs·Jamshid H KarimovKiyotaka Fukamachi

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