PMID: 9001668Dec 1, 1996Paper

Down syndrome and coeliac disease: usefulness of antigliadin and antiendomysium antibodies

Acta Paediatrica
M BonamicoG Gemme

Abstract

The usefulness of antigliadin (AGA) and antiendomysium antibodies (EMA) as a screening test for coeliac disease (CD) in 113 Down syndrome (DS) patients (61 children) was evaluated. AGA IgA were present in 22.1%, AGA IgG in 48.6%, EMA in 6.2%. Four symptomatic patients, AGA- and EMA-positive, were affected by CD (3.5%). In three AGA-positive and EMA-positive subjects, permission for intestinal biopsy was refused, while in two AGA-positive and EMA-negative children, the intestinal mucosa was normal. Our study confirms the association of CD and DS, and suggests the usefulness of EMA determination as a test for selecting DS patients for intestinal biopsy.

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Oct 1, 1994·Acta Paediatrica Japonica; Overseas Edition·K L ReicheltH Scott
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Citations

Jan 3, 2001·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·L SalurR Uibo
Sep 25, 2001·Journal of Pediatric Gastroenterology and Nutrition·M BonamicoUNKNOWN SIGEP (Italian Society of Pediatric Gastroenterology and Hepatology) and Medical Genetic Group
Feb 9, 2005·Journal of Pediatric Gastroenterology and Nutrition·Tony HanssonAnders Dannaeus
Dec 19, 2013·Scandinavian Journal of Gastroenterology·Giuliana GiardinoClaudio Pignata
Aug 13, 2003·Pediatrics International : Official Journal of the Japan Pediatric Society·Ozgur CoguluCihangir Ozkinay
Jun 21, 2013·Alimentary Pharmacology & Therapeutics·J Y KangK Y Ho
Oct 22, 2008·International Review of Neurobiology·Mark S Yerby
Sep 27, 2005·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·F CataldoG Corsello
Aug 13, 1999·The American Journal of Gastroenterology·F BiagiP J Ciclitira
Nov 4, 2008·Journal of Pediatric Gastroenterology and Nutrition·Margherita BonamicoUNKNOWN Società Italiana di Gastroenterologica, Epatologia, e Nutrizione Pediatrica
Mar 26, 2003·European Journal of Pediatrics·Antonín KolekMartin Tichý

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