Downstream Consequences of Exercise Through the Action of BDNF

Brain Plasticity
Sama F Sleiman, Moses V Chao

Abstract

Physical exercise produces many beneficial responses in the brain, which affect cognitive function, blood flow, neurogenesis and resistance to injury. However, the exact mechanisms whereby exercise produces an induction in the brain are not well understood. A significant consequence is the induction of growth factors, such as Brain-derived Neurotrophic Factor (BDNF). Cognitive decline that occurs with aging, as well as progression of neurodegenerative diseases, are strongly correlated with decreases in BDNF. In this article, we discuss the properties of neurotrophins and the mechanisms that can account for the ability of exercise to promote brain plasticity through BDNF.

References

Jan 1, 1990·Progress in Growth Factor Research·Y A Barde
Oct 27, 1995·Science·H Thoenen
Jan 12, 1995·Nature·S A NeeperC Cotman
Oct 12, 1999·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·A Russo-NeustadtC W Cotman
Nov 11, 1999·Proceedings of the National Academy of Sciences of the United States of America·H van PraagF H Gage
Apr 4, 2001·The European Journal of Neuroscience·F Gómez-PinillaV R Edgerton
Jan 10, 2002·Neuron·Moses V Chao, Mark Bothwell
Jun 28, 2002·Trends in Neurosciences·Carl W Cotman, Nicole C Berchtold
Nov 19, 2004·The European Journal of Neuroscience·Shoshanna VaynmanFernando Gomez-Pinilla
Jan 18, 2005·Neurobiology of Aging·Paul A AdlardCarl W Cotman
Apr 29, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Paul A AdlardCarl W Cotman
May 17, 2005·Gene Expression·Victoria M PerreauCarl W Cotman
Jan 18, 2006·Brain Research·Shoshanna S VaynmanFernando Gomez-Pinilla
Aug 19, 2007·Behavioural Brain Research·Kathryn E NicholCarl W Cotman
Sep 4, 2007·Trends in Neurosciences·Carl W CotmanLori-Ann Christie
Jan 1, 2008·Experimental Neurology·Monica M SiegenthalerHans S Keirstead
Jun 6, 2009·Nature Reviews. Neurology·Chiara Zuccato, Elena Cattaneo
Jun 30, 2009·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Kathryn NicholCarl W Cotman
Aug 12, 2009·Experimental Physiology·Peter RasmussenHenriette Pilegaard
Nov 11, 2009·Brain Research·Naoki TajiriIsao Date
Mar 12, 2010·Neuroscience·N C BerchtoldC W Cotman
Mar 13, 2012·Pharmacological Reviews·Anita E Autry, Lisa M Monteggia
Dec 21, 2012·Nature Reviews. Neuroscience·Hyungju Park, Mu-ming Poo
Apr 26, 2013·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Karlie A IntlekoferCarl W Cotman
Jul 9, 2013·Neuropharmacology·Debabrata Panja, Clive R Bramham
Oct 15, 2013·Cell Metabolism·Christiane D WrannBruce M Spiegelman
Feb 20, 2014·Frontiers in Aging Neuroscience·Shikha SnigdhaCarl W Cotman
Nov 26, 2014·Neural Regeneration Research·Shane V HegartyAideen M Sullivan
Jun 5, 2015·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Liang WangMu-ming Poo

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Citations

Feb 13, 2019·Journal of Neural Transmission·Mohammad AlwardatAntonio Pisani
Apr 20, 2019·The Physician and Sportsmedicine·Paul D Loprinzi
May 23, 2020·Molecular Psychiatry·Revathy U ChottekalapandaPaul Greengard
Jun 29, 2016·Brain Plasticity·Fredrick John Seil
Feb 26, 2016·Brain : a Journal of Neurology·Emrah DuzelMichael Sendtner
Oct 9, 2015·Brain Plasticity·Henriette van Praag, Brian Christie
Jan 17, 2019·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Nabil KarnibSama F Sleiman
Feb 20, 2019·Trends in Cognitive Sciences·Michelle W VossHenriette van Praag
Dec 4, 2019·Aging and Disease·Piotr GronekFang Yu
Aug 28, 2021·International Journal of Molecular Sciences·Daniel RibeiroPaula Tavares

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Methods Mentioned

BETA
histone acetylation

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