Draft genome assemblies and predicted microRNA complements of the intertidal lophotrochozoans Patella vulgata (Mollusca, Patellogastropoda) and Spirobranchus (Pomatoceros) lamarcki (Annelida, Serpulida)

Marine Genomics
Nathan J KennySebastian M Shimeld

Abstract

MicroRNAs (miRNA) are small non-coding RNAs that act post-transcriptionally to regulate gene expression levels. Some studies have indicated that microRNAs may have low homoplasy, and as a consequence the phylogenetic distribution of microRNA families has been used to study animal evolutionary relationships. Limited levels of lineage sampling, however, may distort such analyses. Lophotrochozoa is an under-sampled taxon that includes molluscs, annelids and nemerteans, among other phyla. Here, we present two novel draft genomes, those of the limpet Patella vulgata and polychaete Spirobranchus (Pomatoceros) lamarcki. Surveying these genomes for known microRNAs identifies numerous potential orthologues, including a number that have been considered to be confined to other lineages. RT-PCR demonstrates that some of these (miR-1285, miR-1287, miR-1957, miR-1983 and miR-3533), previously thought to be found only in vertebrates, are expressed. This study provides genomic resources for two lophotrochozoans and reveals patterns of microRNA evolution that could be hidden by more restricted sampling.

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Citations

Mar 19, 2016·PeerJ·Umberto RosaniPaola Venier
Nov 12, 2015·Marine Genomics·Maria Ina Arnone, Andreas Hejnol
Feb 17, 2017·Genome Biology and Evolution·Tilman SchellMarkus Pfenninger
Mar 25, 2017·Genome Biology and Evolution·Yongbo BaoSebastian M Shimeld
Mar 19, 2016·Journal of Developmental Biology·Marco BaruccaMaria Assunta Biscotti
Dec 16, 2020·Genome Biology and Evolution·Rebecca M VarneyKevin M Kocot
Apr 6, 2021·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Umberto RosaniBastian Fromm

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