Draft genome of the Chinese mitten crab, Eriocheir sinensis

GigaScience
Linsheng SongPao Xu

Abstract

The Chinese mitten crab, Eriocheir sinensis, is one of the most studied and economically important crustaceans in China. Its transition from a swimming to a crawling method of movement during early development, anadromous migration during growth, and catadromous migration during breeding have been attractive features for research. However, knowledge of the underlying molecular mechanisms that regulate these processes is still very limited. A total of 258.8 gigabases (Gb) of raw reads from whole-genome sequencing of the crab were generated by the Illumina HiSeq2000 platform. The final genome assembly (1.12 Gb), about 67.5 % of the estimated genome size (1.66 Gb), is composed of 17,553 scaffolds (>2 kb) with an N50 of 224 kb. We identified 14,436 genes using AUGUSTUS, of which 7,549 were shown to have significant supporting evidence using the GLEAN pipeline. This gene number is much greater than that of the horseshoe crab, and the annotation completeness, as evaluated by CEGMA, reached 66.9 %. We report the first genome sequencing, assembly, and annotation of the Chinese mitten crab. The assembled draft genome will provide a valuable resource for the study of essential developmental processes and genetic determination of importan...Continue Reading

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Citations

Sep 18, 2016·Integrative and Comparative Biology·Donald L MyklesJonathon H Stillman
Sep 4, 2019·Molecular Ecology Resources·Solomon T C Chak, Dustin R Rubenstein
Apr 25, 2019·Proceedings. Biological Sciences·Joanna M WolfeHeather D Bracken-Grissom
Jan 11, 2020·BMC Genomics·Wenyan NongKa Hou Chu
Dec 13, 2016·Integrative and Comparative Biology·Sunetra DasDavid S Durica
Jun 12, 2020·General and Comparative Endocrinology·Jan A Veenstra
Mar 23, 2021·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Joanna M WolfeHeather D Bracken-Grissom
Aug 30, 2018·The Journal of Steroid Biochemistry and Molecular Biology·Cameron J HydeTomer Ventura
Jun 9, 2021·Proceedings of the National Academy of Sciences of the United States of America·Solomon T C ChakDustin R Rubenstein
Jul 11, 2021·The Journal of Biological Chemistry·Yue-Hong ZhaoWei-Wei Li

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Datasets Mentioned

BETA
PRJNA305216

Methods Mentioned

BETA
whole-genome shotgun sequencing

Software Mentioned

Platanus
Genescan
GENSCAN1
AUGUSTUS2
Cufflink
LTR
TopHat
Ensembl
FINDER
RepeatMasker

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