Draft Genome Sequence of a New Delhi Metallo-β-Lactamase-5 (NDM-5)-Producing Multidrug-Resistant Escherichia coli Isolate

Genome Announcements
Tom J B de ManBrandi M Limbago

Abstract

A multidrug-resistant Escherichia coli isolate from an abdominal lesion displayed resistance to all β-lactams tested, including carbapenems, in addition to macrolides, fluoroquinolones, and tetracycline. Sequence analyses demonstrated the presence of blaNDM-5 in addition to at least 13 genes and 6 efflux pumps associated with antibiotic resistance.

References

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Citations

Apr 12, 2016·Frontiers in Microbiology·Fangfang ZhangJingyong Sun
Jun 16, 2016·MSphere·Tom J B de Man, Brandi M Limbago
Jul 25, 2019·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Zhengzheng WangFangyou Yu
May 2, 2018·Antimicrobial Resistance and Infection Control·Xi LiYunsong Yu

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Methods Mentioned

BETA
electrophoresis

Software Mentioned

SE
Glimmer
Resfinder
tRNAScan
CLC Genomics Workbench
RNAmmer

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Carbapenems are members of the beta lactam class of antibiotics and are used for the treatment of severe or high-risk bacterial infections. Discover the latest research on carbapenems here.