Draft Genome Sequence of the First Confirmed Isolate of Multidrug-Resistant Mycobacterium tuberculosis in Tasmania

Genome Announcements
Sanjay S GautamRonan F O'Toole

Abstract

The spread of multidrug-resistant (MDR) tuberculosis (TB) has become a major global challenge. In 2016, Tasmania recorded its first known incidence of MDR-TB. Here, we report the draft whole-genome sequence of the Mycobacterium tuberculosis isolate from this case, TASMDR1, and describe single-nucleotide polymorphisms associated with its drug resistance.

References

Dec 24, 2008·Antimicrobial Agents and Chemotherapy·Angela M StarksJames E Posey
Jun 6, 2009·Bioinformatics·Samuel AssefaMatthew Berriman
Jun 10, 2009·Bioinformatics·Heng LiUNKNOWN 1000 Genome Project Data Processing Subgroup
Jan 19, 2010·Bioinformatics·Heng Li, Richard Durbin
Apr 18, 2012·Journal of Computational Biology : a Journal of Computational Molecular Cell Biology·Anton BankevichPavel A Pevzner
Dec 20, 2013·Journal of Clinical Microbiology·Timothy C RodwellAntonino Catanzaro
Feb 8, 2014·Genome Announcements·Munawar SultanaM Anwar Hossain
Jun 4, 2014·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·S O SimonsD van Soolingen
Oct 18, 2014·Genome Announcements·Micheál Mac AogáinRonan F O'Toole
May 12, 2015·Nature Communications·Vegard EldholmFrancois Balloux
May 29, 2015·Genome Medicine·Francesc CollTaane G Clark

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Methods Mentioned

BETA
Profiler

Software Mentioned

SPAdes assembler
SnpEff
SAMtools

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