Nov 1, 1989

Dramatic effects of high-dose intravenous gammaglobulin in each patient with intractable dermatomyositis and polymyositis

No to hattatsu. Brain and development
R MoritaY Fukuyama

Abstract

A high-dose intravenous gamma-globulin (IVGG) therapy was given to two children; one with intractable dermatomyositis (case 1) and the other with polymyositis (case 2). Case 1, a 3-year-6-month-old girl, only poorly responded to the standard oral prednisolone therapy and a pulse therapy with high-dose methyl-prednisolone. This patient showed a complete remission after a course IVGG therapy, 100 mg/kg/day iv. for 5 days, which has been maintained for 6 months up to the present. Case 2, a 13-year-6-month-old girl, also showed little improvement after the oral prednisolone therapy, and transient improvement during plasma exchange therapy. This patient showed fairly good response after three repeated courses of IVGG therapy, but not complete remission.

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Mentioned in this Paper

Dermatomyositis, Childhood Type
Intravenous
Intravenous Therapy
Intravenous Injections
Prednisolone Oral Product
Prednisolone
Plasma Exchange
Cancer Remission
Dermatomyositis
Teens

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